January 25, 2016



Securities and Exchange Commission
100 F Street NE
Washington, DC  20549

RE:	Schedule 13G
	Akebia Therapeutics Inc.
	As of December 31, 2015

Gentlemen:

In  accordance  with  Section  13(d)(5)  of  the  Securities Exchange Act
of  1934,  attached please  find  a  copy  of Schedule  13G for the above
named company showing a change in beneficial ownership  of  10% or more
as of December 31, 2015  filed  on behalf of Eagle Asset Management, Inc.

Very truly yours,



Damian Sousa
Vice President
Chief Compliance Officer
Enclosures

cc:	Office of the Corporate Secretary
	Akebia Therapeutics
	245 First Street
	Suite 1100
	Cambridge, MA 02142















SECURITIES AND EXCHANGE COMMISSION
Washington, D.C.  20549

Schedule 13G

Under the Securities Exchange Act of 1934
(Amendment No.   2    )*


Akebia Therapeutics, Inc
(Name of Issuer)


Common Stock
(Title of Class of Securities)


00972D105
(CUSIP Number)


Check the following box if a fee is being paid with this statement
_____.  (A fee is not required only if the filing person:  (1) has
a previous statement on file reporting beneficial ownership of more
than five percent of the class of securities described in Item 1;
and (2) has filed no amendment subsequent thereto reporting beneficial
ownership of five percent or less of such class.)  (See Rule 13d-7.)

*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class
of securities, and for any subsequent amendment containing information
which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not
be deemed to be "filed" for the purpose of Section 18 of the Securities
Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of
that section of the Act but shall be subject to all other provisions of
the Act (however, see the Notes).















Page 1 of 5 Pages

CUSIP NO. 00972D105                                 13G

1	NAME OF REPORTING PERSON
	S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
	Eagle Asset Management, Inc.      59-2385219

2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*	(A) ______
                                                      	(B) ______

3	SEC USE ONLY

4	CITIZENSHIP OR PLACE OF ORGANIZATION

 	State of Florida

   	NUMBER OF	5  SOLE VOTING POWER
	SHARES                           3,953,107
	BENEFICIALLY		6  SHARED VOTING POWER
	OWNED                             - - -
 	AS OF
  	Dec. 31, 2015		7  SOLE DISPOSITIVE POWER
 	BY EACH                           3,953,107
	REPORTING			8  SHARED DISPOSITIVE POWER
 	PERSON WITH                      - - -

9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

             3,953,107

10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN 	SHARES*
                                                  [_____]

11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

		12.91%

12	TYPE OF REPORTING PERSON*

		IA
_____________________________________________________________
                 *SEE INSTRUCTION BEFORE FILLING OUT!
_____________________________________________________________









Page 2 of 5 Pages
Item 1(a) 	Name of Issuer:

          	Akebia Therapeutics, Inc.


Item 1(b) 	Address of Issuer's Principal Executing Offices:

       	        245 First Street
	   	Suite 1100
     		Cambridge, MA 98121

Item 2(a) 	Name of Person Filing:

         	Eagle Asset Management, Inc.


Item 2(b) 	Address of Principal Business Office:

        	880 Carillon Parkway
          	St. Petersburg, Florida  33716


Item 2(c)	Citizenship:

          	Florida


Item 2(d) 	Title of Class of Securities:

          	Common Stock


Item 2(e)	CUSIP Number:

          	00972D105


Item 3    	Type of Reporting Person:

		(e) Investment Adviser registered under Section 203 of the
 	Investment Advisors Act of 1940












Page 3 of 5 Pages
Item 4	Ownership as of Dec. 31, 2015

	(a)	Amount Beneficially Owned:

           	3,953,107 shares of common stock beneficially owned including:

										No. of Shares
		Eagle Asset Management, Inc.				3,953,107

       (b)  	Percent of Class:						12.91%

       (c)	Deemed Voting Power and Disposition Power:

              	(i)        	(ii)           	(iii)		 (iv)
              Deemed	 Deemed
              	Deemed	Deemed		to have	 to have
              	to have	to have		Sole Power	 Shared Power
              	Sole Power	Shared Power	to Dispose	 to Dispose
              	to Vote or	to Vote or		or to		 or to
              	to Direct	to Direct		Direct the	 Direct the
              	to Vote	to Vote          Disposition	 Disposition

Eagle Asset		3,953,107	----			3,953,107        ----
Management, Inc.


Item 5   	Ownership of Five Percent or Less of a Class:

		If this statement is being filed to report the fact that
as of the date hereof the reporting person has ceased to be the beneficial owner
 of more than five percent of the class of securities, check the following.
             							(____)

Item 6	Ownership of More than Five Percent on Behalf of Another 			Person:

              	 N/A

Item 7   	Identification and Classification of the Subsidiary which
 	Acquired the Security Being Reported on by the Parent Holding Company:

              	 N/A









Page 4 of 5 Pages
Item 8   	Identification and Classification of Members of the Group:
		N/A


Item 9   	Notice of Dissolution of Group:

		 N/A


Item 10  	Certification:

By signing below I certify that to the best of my knowledge
and belief, the securities referred to above were acquired in
the ordinary course of business and were not acquired for purpose
of and do not have the effect of changing or influencing the control
of the issuer of such securities and were not  acquired  in  connection
 with or as a participant in any transaction having such purposes or effect.

         	Signature


After reasonable inquiry and to the best of  my knowledge
and belief, I certify that the information set forth in this
statement is true, complete and correct.

Date: January 25, 2016		EAGLE ASSET MANAGEMENT, INC.


					/s/ Damian Sousa
 					_________________________________
 					Damian Sousa
 					Vice President
 					Chief Compliance Officer


















Page 5 of 5 Pages