PAGE  1
000 A000000 04/30/2008
000 C000000 0000883412
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 BLACKROCK MUNIYIELD INSURED FUND, INC.
001 B000000 811-06540
001 C000000 8004417762
002 A000000 100 BELLEVUE PARKWAY
002 B000000 WILMINGTON
002 C000000 DE
002 D010000 19809
003  000000 N
004  000000 N
005  000000 N
006  000000 N
007 A000000 N
007 B000000  0
007 C010100  1
007 C010200  2
007 C010300  3
007 C010400  4
007 C010500  5
007 C010600  6
007 C010700  7
007 C010800  8
007 C010900  9
007 C011000 10
007 C011100 11
007 C011200 12
007 C011300 13
007 C011400 14
007 C011500 15
007 C011600 16
007 C011700 17
007 C011800 18
007 C011900 19
007 C012000 20
008 A000001 BLACKROCK ADVISORS, LLC
008 B000001 A
008 C000001 801-47710
008 D010001 WILMINGTON
008 D020001 DE
008 D030001 19809
008 A000002 BLACKROCK INVESTMENT MANAGEMENT, LLC
008 B000002 S
008 C000002 801-56972
      PAGE  2
008 D010002 PLAINSBORO
008 D020002 NJ
008 D030002 08536
012 A000001 COMPUTERSHARE TRUST COMPANY, N.A. (COMMON)
012 B000001 85-11340
012 C010001 PROVIDENCE
012 C020001 RI
012 C030001 02940
012 C040001 3010
012 A000002 BNY MELLON SHAREHOLDER SERVICES (PREFERRED)
012 B000002 85-05006
012 C010002 NEW YORK
012 C020002 NY
012 C030002 10286
013 A000001 DELOITTE & TOUCHE LLP
013 B010001 PRINCETON
013 B020001 NJ
013 B030001 08540
014 A000001 MLPF&S AND OTHER ML BROKER/DEALER AFFILIATES
014 B000001 8-7221
014 A000002 BLACKROCK INVESTMENTS, INC.
014 B000002 8-048436
014 A000003 NORTHERN FUNDS DISTRIBUTORS, LLC
014 B000003 8-051242
014 A000004 PNC CAPITAL MARKETS, INC.
014 B000004 8-32493
014 A000005 PFPC DISTRIBUTORS, INC.
014 B000005 8-045467
014 A000006 MGI FUNDS DISTRIBUTOR, INC.
014 B000006 8-046960
014 A000007 BB & T AM DISTRIBUTORS, INC.
014 B000007 8-52396
014 A000008 BLACKROCK DISTRIBUTORS, INC.
014 B000008 8-048775
014 A000009 PNC INVESTMENTS LLC
014 B000009 8-066195
014 A000010 HARRIS WILLIAMS LLC
014 B000010 8-53380
014 A000011 DSP MERRILL LYNCH LIMITED
014 B000011 8-00000
014 A000012 FAM DISTRIBUTORS, INC.
014 B000012 8-14663
014 A000013 FIRST REPUBLIC SECURITIES COMPANY, LLC
014 B000013 8-52973
014 A000014 GPC SECURITIES, INC.
014 B000014 8-30108
014 A000015 BERNDALE SECURITIES LIMITED
014 B000015 8-00000
015 A000001 STATE STREET BANK AND TRUST COMPANY
015 B000001 C
015 C010001 BOSTON
      PAGE  3
015 C020001 MA
015 C030001 02101
015 E010001 X
015 A000002 THE BANK OF NEW YORK MELLON
015 B000002 S
015 C010002 NEW YORK
015 C020002 NY
015 C030002 10286
015 E010002 X
015 A000003 J.P. MORGAN CHASE BANK
015 B000003 S
015 C010003 NEW YORK
015 C020003 NY
015 C030003 10017
015 E010003 X
018  000000 Y
019 A000000 Y
019 B000000  301
019 C000000 BLKRKADVSR
020 A000001 JANNEY MONTGOMERY SCOTT LLC
020 B000001 23-0731260
020 C000001      0
020 C000002      0
020 C000003      0
020 C000004      0
020 C000005      0
020 C000006      0
020 C000007      0
020 C000008      0
020 C000009      0
020 C000010      0
021  000000        0
022 A000001 J.P. MORGAN SECURITIES INC.
022 B000001 13-3224016
022 C000001    364916
022 D000001    230236
022 A000002 MERRILL LYNCH INSTITUTIONAL TAX-EXEMPT FUND
022 B000002 22-2509978
022 C000002    281600
022 D000002    286200
022 A000003 UBS SECURITIES LLC
022 B000003 13-3873456
022 C000003    131608
022 D000003    161123
022 A000004 GOLDMAN, SACHS & CO.
022 B000004 13-5108880
022 C000004    128361
022 D000004    142801
022 A000005 MORGAN STANLEY & CO. INCORPORATED
022 B000005 13-2655998
022 C000005    142143
      PAGE  4
022 D000005    103322
022 A000006 CITIGROUP GLOBAL MARKETS, INC.
022 B000006 11-2418191
022 C000006     85633
022 D000006    111955
022 A000007 BEAR, STEARNS & CO. INC.
022 B000007 13-3299429
022 C000007    125217
022 D000007     52512
022 A000008 MORGAN KEEGAN & COMPANY, INC.
022 B000008 64-0474907
022 C000008     40010
022 D000008     37756
022 A000009 RBC DAIN RAUSCHER INC.
022 B000009 41-0212020
022 C000009     53541
022 D000009     24200
022 A000010 BANC OF AMERICA SECURITIES LLC
022 B000010 56-2058405
022 C000010     25888
022 D000010     50518
023 C000000    1606304
023 D000000    1618147
024  000000 N
026 A000000 N
026 B000000 N
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 N
026 H000000 N
027  000000 N
045  000000 Y
046  000000 N
047  000000 Y
048  000000  0.500
048 A010000        0
048 A020000 0.000
048 B010000        0
048 B020000 0.000
048 C010000        0
048 C020000 0.000
048 D010000        0
048 D020000 0.000
048 E010000        0
048 E020000 0.000
048 F010000        0
048 F020000 0.000
048 G010000        0
      PAGE  5
048 G020000 0.000
048 H010000        0
048 H020000 0.000
048 I010000        0
048 I020000 0.000
048 J010000        0
048 J020000 0.000
048 K010000        0
048 K020000 0.000
049  000000 N
050  000000 N
051  000000 N
052  000000 N
053 A000000 N
054 A000000 Y
054 B000000 Y
054 C000000 N
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 N
054 H000000 Y
054 I000000 N
054 J000000 Y
054 K000000 N
054 L000000 N
054 M000000 Y
054 N000000 N
055 A000000 N
055 B000000 N
056  000000 Y
057  000000 N
058 A000000 N
059  000000 Y
060 A000000 N
060 B000000 N
061  000000        0
062 A000000 Y
062 B000000   0.0
062 C000000   0.0
062 D000000   0.0
062 E000000   6.5
062 F000000   0.0
062 G000000   0.0
062 H000000   0.0
062 I000000   0.0
062 J000000   0.0
062 K000000   0.0
062 L000000   0.0
062 M000000   0.0
062 N000000   0.0
      PAGE  6
062 O000000 175.5
062 P000000   0.0
062 Q000000   0.0
062 R000000   0.0
063 A000000   0
063 B000000 24.3
064 A000000 Y
064 B000000 N
066 A000000 N
067  000000 N
068 A000000 N
068 B000000 N
069  000000 N
070 A010000 Y
070 A020000 N
070 B010000 N
070 B020000 N
070 C010000 Y
070 C020000 N
070 D010000 N
070 D020000 N
070 E010000 Y
070 E020000 N
070 F010000 N
070 F020000 N
070 G010000 Y
070 G020000 N
070 H010000 N
070 H020000 N
070 I010000 N
070 I020000 N
070 J010000 N
070 J020000 N
070 K010000 Y
070 K020000 Y
070 L010000 N
070 L020000 N
070 M010000 N
070 M020000 N
070 N010000 Y
070 N020000 N
070 O010000 Y
070 O020000 N
070 P010000 Y
070 P020000 Y
070 Q010000 N
070 Q020000 N
070 R010000 N
070 R020000 N
071 A000000    800730
071 B000000    841628
      PAGE  7
071 C000000   1594808
071 D000000   50
072 A000000  6
072 B000000    38249
072 C000000      194
072 D000000        0
072 E000000        0
072 F000000     3748
072 G000000      162
072 H000000        0
072 I000000       50
072 J000000       35
072 K000000        0
072 L000000       28
072 M000000       46
072 N000000       11
072 O000000        0
072 P000000     2796
072 Q000000        0
072 R000000       23
072 S000000       63
072 T000000        0
072 U000000        0
072 V000000        0
072 W000000      793
072 X000000     7755
072 Y000000       15
072 Z000000    30703
072AA000000    14467
072BB000000    34579
072CC010000        0
072CC020000    49629
072DD010000    22614
072DD020000        0
072EE000000        0
073 A010000   0.3360
073 A020000   0.0000
073 B000000   0.0000
073 C000000   0.0000
074 A000000        6
074 B000000        0
074 C000000    59212
074 D000000  1593423
074 E000000        0
074 F000000        0
074 G000000        0
074 H000000        0
074 I000000      313
074 J000000    27888
074 K000000        0
074 L000000    20629
      PAGE  8
074 M000000       30
074 N000000  1701501
074 O000000    88005
074 P000000      610
074 Q000000        0
074 R010000        0
074 R020000        0
074 R030000        0
074 R040000   133955
074 S000000   570533
074 T000000   908398
074 U010000    67303
074 U020000        0
074 V010000    13.50
074 V020000     0.00
074 W000000   0.0000
074 X000000    27987
074 Y000000   635174
075 A000000        0
075 B000000  1507424
076  000000    12.90
077 A000000 Y
077 O000000 Y
078  000000 N
086 A010000      0
086 A020000      0
086 B010000      0
086 B020000      0
086 C010000      0
086 C020000      0
086 D010000      0
086 D020000      0
086 E010000      0
086 E020000      0
086 F010000      0
086 F020000      0
087 A010000 COMMON STOCK
087 A020000 09254E103
087 A030000 MYI
087 B010000 PREFERRED STOCK
088 A000000 N
088 B000000 N
088 C000000 N
088 D000000 Y
SIGNATURE   DONALD C. BURKE
TITLE       PRESIDENT