Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
HOLIFIELD MARK
  2. Issuer Name and Ticker or Trading Symbol
OFFICE DEPOT INC [ODP]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
EVP - Supply Chain
(Last)
(First)
(Middle)
2200 OLD GERMANTOWN ROAD, MAIL CODE: LEGL
3. Date of Earliest Transaction (Month/Day/Year)
02/24/2006
(Street)

DELRAY BEACH, FL 33445
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 02/24/2006   M   5,002 A $ 12.5 27,908 D  
Common Stock 02/24/2006   M   20,000 A $ 11.02 47,908 D  
Common Stock 02/24/2006   S   1,200 D $ 35.58 46,708 D  
Common Stock 02/24/2006   S   2,700 D $ 35.59 44,008 D  
Common Stock 02/24/2006   S   16,400 D $ 35.6 27,608 D  
Common Stock 02/24/2006   S   4,702 D $ 35.61 22,906 (1) D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option (Right to Buy) $ 12.5 02/24/2006   M     5,002 06/23/1997 06/23/2007 Common Stock 5,002 $ 0 0 D  
Option (Right to Buy) $ 11.02 02/24/2006   M     20,000 07/25/1998 07/25/2007 Common Stock 20,000 $ 0 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
HOLIFIELD MARK
2200 OLD GERMANTOWN ROAD
MAIL CODE: LEGL
DELRAY BEACH, FL 33445
      EVP - Supply Chain  

Signatures

 By: Anne Zuckerman, Attorney-in-Fact for:   02/28/2006
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Beneficial holdings on Table I is updated to include 360 total shares in the Employee Stock Purchase Plan; 844 total shares in the 401(k); and 4295 total shares under a Deferred Compensation Plan as of 2/14/2006.

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