PROSPECTUS

This  prospectus  is not an offer to sell or a  solicitation  of an offer to buy
these securities in any state where the offer or sale is not permitted.

                               VASOMEDICAL, INC.

                    up to 10,787,871 Shares of Common Stock

     This is an offering of shares of common stock of Vasomedical,  Inc. Certain
of our  stockholders,  referred to as selling  securityholders  throughout  this
document,  are offering to sell up to 10,787,871 shares of common stock. We will
not receive any proceeds from the sale of shares by the selling securityholders,
which include:

     Up to 8,533,333 shares issuable in connection with conversion of our Series
     D Convertible Preferred Stock

     Up to  2,254,538  shares  issuable  upon the  exercise of our common  stock
     purchase warrants

     All of the shares being offered by this prospectus are being offered by the
selling  securityholders  named in this  prospectus.  This offering is not being
underwritten.  We will  not  receive  any of the  proceeds  from the sale of the
shares of our common stock in this  offering.  If the warrants are  exercised so
that the  underlying  shares may be sold, we will receive the exercise  price of
the warrants,  which currently is $0.6936 per share. The selling securityholders
identified in this prospectus,  or their pledges,  donees,  transferees or other
successors-in-interest,  may offer the common  stock or  interests  therein from
time to time through public or private transactions at prevailing market prices,
at prices  related to  prevailing  market  prices,  or at  privately  negotiated
prices. We will pay all expenses of registering this offering of securities.

     The common stock is traded on the Nasdaq  SmallCap  Market System under the
symbol VASO.  On August 16,  2005,  the last  reported  sale price of the common
stock as reported by the Nasdaq SmallCap Market System was $0.58 per share.


INVESTING IN OUR COMMON STOCK INVOLVES  RISKS.  SEE 'RISK FACTORS'  BEGINNING ON
PAGE 4.

NEITHER THE SECURITIES AND EXCHANGE COMMISSION NOR ANY OTHER REGULATORY BODY HAS
APPROVED OR  DISAPPROVED  OF THESE  SECURITIES  OR PASSED  UPON THE  ACCURACY OR
ADEQUACY  OF THE  PROSPECTUS.  ANY  REPRESENTATIONS  MADE TO THE  CONTRARY  IS A
CRIMINAL OFFENSE.

                THE DATE OF THIS PROSPECTUS IS SEPTEMBER 1, 2005




                               TABLE OF CONTENTS
                                                                         Page



RISK FACTORS                                                               4
Risks Related to Our Business                                              4
Risks Related to Our Industry                                              7
Risks Related to Stock Exchange and SEC Regulation                         8
FORWARD-LOOKING STATEMENTS                                                10
USE OF PROCEEDS                                                           10
RECENT SALES OF UNREGISTERED SECURITIES                                   11
SELLING SECURITYHOLDERS                                                   12
PLAN OF DISTRIBUTION                                                      14
DESCRIPTION OF OUR SECURITIES                                             16
Capital Stock                                                             16
Common Stock                                                              16
Undesignated Preferred Stock                                              16
Series D Convertible Preferred Stock                                      17
LEGAL MATTERS                                                             17
EXPERTS                                                                   17
DISCLOSURE OF COMMISSION POSITION ON INDEMNIFICATION 
   FOR SECURITIES ACT LIABILITIES                                         18
WHERE YOU CAN FIND MORE INFORMATION                                       18
INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE                           18

                                       2


                             ----------------------

You should rely only on the  information  contained in this document or to which
we have  referred  you.  We have  not  authorized  anyone  to  provide  you with
information that is different.  This document may only be used where it is legal
to sell these securities.  The information in this document may only be accurate
on the date of this document.

As used in this prospectus,  the terms "we," "us," "our," and "Vasomedical" mean
Vasomedical, Inc. and its subsidiaries, unless we specify otherwise.

We are  incorporated  under the laws of the  state of  Delaware.  Our  executive
offices  are  located at 180  Linden  Avenue,  Westbury,  New York 11590 and our
telephone number is (516) 997-4600.

EECP(R) is our  registered  trademark.  All other  trademarks  mentioned in this
prospectus are the property of their respective owners.

                                       3



                                  RISK FACTORS

     You  should  carefully  consider  the  factors  described  below  and other
information  contained in this  prospectus  before  making a decision to buy our
common stock. The risks and uncertainties  described below are not the only ones
we face.  Additional risks and uncertainties not presently known to us, which we
currently deem immaterial or which are similar to those faced by other companies
in our industry or business in general, may also impair our business operations.
If any of the following risks actually occurs, our business, financial condition
or results of future operations could be materially and adversely  affected.  In
such case, the trading price of our common stock could decline, and you may lose
all or part of your  investment.  This prospectus also contains  forward-looking
statements   that   involve   risks   and   uncertainties.   Please   refer   to
"Forward-Looking Statements" on page 10.

Risks Related to Our Business

We are materially  dependent on medical  reimbursement for treatment  procedures
using EECP therapy on patients with congestive heart failure in order to achieve
continued growth.

     We are currently  dependent on a single product  platform  which,  based on
current medical reimbursement policies, provides coverage for a restricted class
of heart  patients.  While we have been engaged in discussions  with the Centers
for  Medicare and  Medicaid  Services to expand the class of heart  patients for
medical coverage,  we are uncertain as to the outcome of these meetings. We also
have been engaged in certain  clinical  trials for the purpose of expanding this
coverage,  most  notable  being our PEECH  clinical  trial.  Our  business  plan
projects  that the  results  could  substantially  expand the number of patients
available  for  medical  reimbursement.  However  Medicare,  Medicaid  and other
third-party payers may deny expansion of reimbursement coverage if they feel the
data from the PEECH clinical trial and other clinical  studies is not sufficient
to  support a  positive  coverage  decision.  On May 31,  2005 we  submitted  an
application to CMS to expand the national  coverage policy for EECP treatment to
include, among other patients,  patients with congestive heart failure (CHF). If
we do not receive medical  coverage for treatment  procedures using EECP therapy
on patients with CHF, it will adversely affect our future business prospects.

Material  changes in the  availability  of  Medicare,  Medicaid  or  third-party
reimbursement at adequate price levels could adversely affect our business.

     Health care providers,  such as hospitals and physician private  practices,
that purchase or lease medical  devices such as the EECP therapy  system for use
on their patients generally rely on third-party  payers,  principally  Medicare,
Medicaid and private  health  insurance  plans,  to reimburse all or part of the
costs and fees associated with the procedures  performed with these devices.  If
there were any material  change in the  availability  of  Medicare,  Medicaid or
other  third-party  coverage  or the  adequacy  of the  reimbursement  level for
treatment  procedures  using the EECP therapy system,  it would adversely affect
our business,  financial condition and results of operations.  Moreover,  we are
unable to forecast what additional  legislation or regulation,  if any, relating
to the health care  industry or Medicare or Medicaid  coverage and payment level
may be enacted in the future or what effect such legislation or regulation would
have on our business. Even if a device has FDA clearance, Medicare, Medicaid and
other third-  party  payers may deny  reimbursement  if they  conclude  that the
device  is not  cost-effective,  is  experimental  or is used for an  unapproved
indication.  In addition,  reimbursement may not be at or remain at price levels
adequate to allow medical  professionals and hospitals to realize an appropriate
return on the purchase of our products.

                                       4


Increased acceptance by the medical community is important for continued growth.


     While many  abstracts and  publications  are  presented  each year at major
scientific meetings worldwide with respect to EECP treatment efficacy,  there is
continued  skepticism  concerning EECP therapy  methodology.  The American Heart
Association and the American College of Cardiology Practice Guidelines currently
list EECP as a therapy  currently  under  investigation  for  treatment of heart
failure and have a classification  rating of IIb as a treatment for patients who
are  refractory  to medical  therapy  and are not  candidates  for  percutaneous
intervention or revascularization.  A classification rating of IIb indicates the
usefulness/efficacy    of   EECP   therapy   is   less   well   established   by
evidence/opinion.   The  medical   community   utilizes  these  guidelines  when
considering  the  various   treatment   options  for  their  patients.   Certain
cardiologists,  in cases where the EECP therapy is a viable  alternative,  still
appear to prefer percutaneous  coronary  interventions (e.g. balloon angioplasty
and stenting) and cardiac bypass surgery for their patients. Additional evidence
regarding the efficacy of EECP therapy continues to evolve, however the evidence
may not be sufficient to warrant a  modification  of these  guidelines to a more
favorable  recommendation and increased acceptance by the medical community.  We
are dependent on consistency of favorable  research  findings about EECP therapy
and  increasing  acceptance  of EECP  therapy  as a  safe,  effective  and  cost
effective  alternative to other available  products by the medical community for
continued growth.

We face competition from other companies and technologies.

     We compete with at least three other companies that are marketing  external
counterpulsation  devices.  We do not  know  whether  these  companies  or other
potential competitors who may be developing external  counterpulsation  devices,
may succeed in developing  technologies or products that are more efficient than
those offered by us, and that would render our technology and existing  products
obsolete  or   non-competitive.   Potential  new   competitors   may  also  have
substantially greater financial manufacturing and marketing resources than those
possessed by us. In addition,  other  technologies  or products may be developed
that have an entirely  different approach or means of accomplishing the intended
purpose  of our  products.  Accordingly,  the life  cycles of our  products  are
difficult  to  estimate.  To  compete  successfully,  we  must  keep  pace  with
technological  advancements,  respond  to  evolving  consumer  requirements  and
achieve market acceptance.

We may not continue to receive  necessary FDA  clearances  or  approvals,  which
could hinder our ability to market and sell our products.

     If we modify our external  counterpulsation  devices and the  modifications
significantly  affect  safety  or  effectiveness,  or if we make a change to the
intended  use,  we will be required to submit a new  premarket  notification  or
510(k) to FDA. We would be unable to market the modified device until FDA issues
a clearance for the 510(k).

     Additionally,  if FDA publishes a regulation requiring a premarket approval
application or PMA for external  counterpulsation devices, we would then need to
submit a PMA, and have it filed by the agency,  by the date  specified by FDA in
its  regulation.  A PMA requires us to prove the safety and  effectiveness  of a
device to the FDA. The process of obtaining  PMA  approval is  expensive,  time-
consuming,  and uncertain.  If FDA were to require a PMA application,  we likely
would be required to undertake a clinical study,  which likely will be expensive
and require lengthy  follow-up,  to demonstrate the effectiveness of the device.
If we did obtain PMA approval, any change after approval affecting the safety or
effectiveness of the device will require approval of a PMA supplement.

     If we offer new products that require 510(k) clearance or PMA approval,  we
will not be able to commercially distribute those products until we receive such
clearance or approval. Regulatory agency approval or clearance for a product may

                                       5


not be received or may entail  limitations on the device's  indications  for use
that could limit the potential  market for any such  product.  Delays in receipt
of, or failure to obtain or maintain, regulatory clearances and approvals, could
delay or prevent our ability to market or distribute  our products.  Such delays
could have a material adverse effect on our business.

If we are unable to comply with applicable governmental  regulation,  we may not
be able to continue our operations.

     We also must  comply  with  Current  Good  Manufacturing  Practices  (CGMP)
requirements as set forth in the Quality System Regulations (QSR) to receive FDA
approval to market new products and to continue to market current products.  The
QSR imposes certain procedural and documentation requirements on us with respect
to manufacturing and quality assurance activities, including packaging, storage,
and recordkeeping. Our products and activities are subject to extensive, ongoing
regulation,  including  regulation  of labeling  and  promotion  activities  and
adverse event  reporting.  Also,  our FDA  registered  facilities are subject to
inspection by the FDA and other governmental authorities.  Any failure to comply
with  regulatory  requirements  could  delay or prevent our ability to market or
distribute our products.  Violation of FDA statutory or regulatory  requirements
could result in  enforcement  actions,  such as voluntary or mandatory  recalls,
suspension  or  withdrawal  of  marketing  clearances  or  approvals,  seizures,
injunctions,  fines, civil penalties,  and criminal  prosecutions,  all of which
could have a material  adverse  effect on our  business.  Most  states also have
similar postmarket regulatory and enforcement authority for devices.

     We  cannot   predict   the   nature  of  any  future   laws,   regulations,
interpretations,  or  applications,  nor can we predict  what effect  additional
governmental  regulations or  administrative  orders,  when and if  promulgated,
would have on our  business  in the future.  We may be slow to adapt,  or we may
never adapt to changes in existing  requirements or adoption of new requirements
or policies.  We may incur significant costs to comply with laws and regulations
in the future or compliance with laws or regulations may create an unsustainable
burden on our business.

We may not  receive  approvals  by foreign  regulators  that are  necessary  for
international sales.

     Sales of medical  devices  outside the United States are subject to foreign
regulatory requirements that vary from country to country. Premarket approval or
clearance  in the United  States  does not ensure  regulatory  approval by other
jurisdictions.  If we,  or any  international  distributor,  fail to  obtain  or
maintain  required   pre-market   approvals  or  fail  to  comply  with  foreign
regulations,  foreign  regulatory  authorities  may  require us to file  revised
governmental  notifications,  cease  commercial  sales  of our  products  in the
applicable  countries or otherwise cure the problem.  Such enforcement action by
regulatory authorities may be costly.

     In order to sell our  products  within the European  Union,  we must comply
with the  European  Union's  Medical  Device  Directive.  The CE  marking on our
products attests to this  compliance.  Future  regulatory  changes may limit our
ability to use the CE mark,  and any new products we develop may not qualify for
the CE mark. If we lose this  authorization  or fail to obtain  authorization on
future products, we will not be able to sell our products in the European Union.

We may not be able to manage growth.

     If our short and  long-term  plans are  successful,  including our clinical
trials,  we will  experience  a period of growth that could place a  significant
strain  upon  our   managerial,   financial  and  operational   resources.   Our

                                       6


infrastructure, procedures, controls and information systems may not be adequate
to support  our  operations  and to achieve  the rapid  execution  necessary  to
successfully market our products.  Our future operating results will also depend
on our ability to  successfully  upgrade  our  information  systems,  expand our
direct sales force and our internal  sales,  marketing and support staff.  If we
are unable to manage future  expansion  effectively,  our  business,  results of
operations and financial  condition will suffer,  our senior  management will be
less effective, and our revenues and product development efforts may decrease.

We depend on management and other key personnel.

     We are  dependent  on a limited  number  of key  management  and  technical
personnel. The loss of one or more of our key employees may hurt our business if
we are unable to identify other individuals to provide us with similar services.
We do not maintain "key person" insurance on any of our employees.  In addition,
our success  depends  upon our ability to attract and retain  additional  highly
qualified  sales,   management,   manufacturing  and  research  and  development
personnel.  We face competition in our recruiting activities and may not be able
to attract or retain qualified personnel.

We may not have adequate intellectual property protection.

     Our  patents  and  proprietary  technology  may  not  be  able  to  prevent
competition by others.  The validity and breadth of claims in medical technology
patents involve complex legal and factual questions.  Future patent applications
may  not be  issued,  the  scope  of  any  patent  protection  may  not  exclude
competitors,  and our patents may not provide competitive  advantages to us. Our
patents may be found to be invalid and other  companies  may claim  rights in or
ownership  of the patents and other  proprietary  rights held or licensed by us.
Also, our existing patents may not cover products that we develop in the future.
Moreover,  when our patents expire, the inventions will enter the public domain.
There can be no  assurance  that our  patents  will not be  violated or that any
issued  patents  will  provide  protection  that  has  commercial  significance.
Litigation may be necessary to protect our patent position.  Such litigation may
be costly  and  time-consuming,  and there can be no  assurance  that we will be
successful in such litigation.

The loss or  violation  of certain of our  patents and  trademarks  could have a
material adverse effect upon our business.

     Since patent  applications  in the United States are  maintained in secrecy
until patents are issued, our patent  applications may infringe patents that may
be issued to others.  If our  products  were found to infringe  patents  held by
competitors, we may have to modify our products to avoid infringement, and it is
possible that our modified products would not be commercially successful.

We do not intend to pay dividends in the foreseeable future.

     We do not  intend  to pay any cash  dividends  on our  common  stock in the
foreseeable future.

Risks Related to Our Industry

Technological change is difficult to predict and to manage.

     We face the challenges that are typically faced by companies in the medical
device  field.  Our product  line has  required,  and any future  products  will
require,  substantial  development  efforts  and  compliance  with  governmental
clearance or approval requirements. We may encounter unforeseen technological or
scientific  problems  that  force  abandonment  or  substantial  change  in  the
development of a specific product or process.

                                       7


We are subject to product liability claims and product recalls that may not be
covered by insurance.

     The nature of our business exposes us to risks of product  liability claims
and product  recalls.  Medical devices as complex as ours frequently  experience
errors or failures,  especially  when first  introduced or when new versions are
released.

     We  currently  maintain  product  liability  insurance  at  $7,000,000  per
occurrence and $7,000,000 in the aggregate.  Our product liability insurance may
not be  adequate.  In the future,  insurance  coverage  may not be  available on
commercially reasonable terms, or at all. In addition,  product liability claims
or  product  recalls  could  damage  our  reputation  even if we  have  adequate
insurance coverage.

We do not know the effects of healthcare reform proposals.

     The healthcare  industry is undergoing  fundamental  changes resulting from
political   economic  and   regulatory   influences.   In  the  United   States,
comprehensive  programs  have  been  suggested  seeking  to  increase  access to
healthcare for the uninsured,  control the escalation of healthcare expenditures
within the  economy  and use  healthcare  reimbursement  policies to balance the
federal budget.

        We expect that the United States Congress and state legislatures will
continue to review and assess various healthcare reform proposals, and public
debate of these issues will likely continue. There have been, and we expect that
there will continue to be, a number of federal and state proposals to constrain
expenditures for medical products and services, which may affect payments for
products such as ours. We cannot predict which, if any of such reform proposals
will be adopted and when they might be effective, or the effect these proposals
may have on our business. Other countries also are considering health reform.
Significant changes in healthcare systems could have a substantial impact on the
manner in which we conduct our business and could require us to revise our
strategies.

Risks Related to Stock Exchange and SEC Regulation

A continued  stock price below $1 could result in our being  de-listed  from the
Nasdaq and  subject us to  regulations  that could  reduce our  ability to raise
funds.

     By letter dated May 2, 2005, we received written  notification  from Nasdaq
that the bid price of our common stock for the last 30 consecutive business days
had closed below the minimum $1.00 per share  required for  continued  inclusion
under  Marketplace  Rule 4310(c) (4) (the Rule). In accordance with  Marketplace
Rule 4310 (c) (d), we have been provided an initial  period of 180 calendar days
of until October 31, 2005, to regain compliance. If at any time before that date
the bid  price of our  common  stock  closes  at $1.00  per  share or more for a
minimum  of  10  consecutive   business  days,  we  will  be  provided   written
notification that it is in compliance with the Rule.

     Further, if we are not in compliance with the Rule by October 31, 2005, and
we meet the Nasdaq SmallCap  initial  listing  criteria except for the bid price
requirement,  we will be granted an  additional  180 calendar  days to April 29,
2006 to comply.  In this regard,  we currently  meet all of the initial  listing
criteria except for the bid price requirement.

     Nasdaq's notification further provides that in the event we were to receive
written notification that our securities will be delisted, we maintain our right
to appeal such determination to a Listing Qualifications Panel.

     Ultimately,  non-compliance  could  result in Nasdaq  delisting  our common
stock.  Such  delisting  could have an adverse  effect on the  liquidity  of our

                                       8



common  stock and could also  impact  our  ability  to raise  additional  equity
capital, if necessary.

     In the event that our common stock was de-listed  from the Nasdaq  SmallCap
Market due to low stock price,  we may become subject to special  rules,  called
penny  stock  rules  that  impose  additional  sales  practice  requirements  on
broker-dealers who sell our common stock. The rules require, among other things,
the delivery, prior to the transaction, of a disclosure schedule required by the
Securities and Exchange  Commission relating to the market for penny stocks. The
broker-dealer   also  must  disclose  the   commissions   payable  both  to  the
broker-dealer and the registered  representative  and current quotations for the
securities,  and  monthly  statements  must  be  sent  disclosing  recent  price
information.

     In the event that our common stock becomes  characterized as a penny stock,
our market  liquidity could be severely  affected.  The regulations  relating to
penny stocks could limit the ability of broker- dealers to sell our common stock
and thus the  ability of  purchasers  of our common  stock to sell their  common
stock in the secondary market.

We are subject to stock exchange and SEC regulation.

     Recent  Sarbanes-Oxley  legislation  and stock  exchange  regulations  have
increased  disclosure control,  financial  reporting,  corporate  governance and
internal control  requirements  that will increase the  administrative  costs of
documenting  and auditing  internal  processes,  gathering  data,  and reporting
information.  Our inability to comply with the requirements would  significantly
impact our market valuation.

Our common stock is subject to price volatility.

     The market  price of our common stock has been and is likely to continue to
be highly  volatile.  Our stock price could be subject to wide  fluctuations  in
response to various factors beyond our control, including:

     --   quarterly variations in operating results;
     --   announcements of technological innovations, new products or pricing by
          our competitors;
     --   the rate of adoption by physicians of our  technology  and products in
          targeted markets;
     --   the timing of patent and regulatory approvals;
     --   medical reimbursement;
     --   the timing and extent of technological advancements;
     --   results of clinical studies;
     --   the sales of our common stock by affiliates or other shareholders with
          large holdings; and
     --   general market conditions.

     Our future operating  results may fall below the expectations of securities
industry analysts or investors. Any such shortfall could result in a significant
decline in the market price of our common stock.  In addition,  the stock market
has experienced significant price and volume fluctuations that have affected the
market price of the stock of many medical  device  companies and that often have
been  unrelated to the  operating  performance  of such  companies.  These broad
market fluctuations may directly influence the market price of our common stock.

Recent corporate  scandals  involving  alleged  accounting  irregularities  have
resulted in  unavailability  of, or significantly  higher premiums for, director
and officer liability insurance.

     As a result of recent  well-publicized  corporate business failures alleged
to have  involved  improper acts by executives  and  accounting  irregularities,
director and officer liability insurance has become more difficult to obtain and

                                       9


the premiums for such insurance have increased  significantly.  If we are unable
to obtain director and officer liability  insurance at rates that are reasonable
or at all, we may not be able to retain our current  officers  and  directors or
attract qualified directors and officers in the future.

Additional Information

     We are subject to the reporting  requirements under the Securities Exchange
Act of 1934 and are required to file reports and information with the Securities
and Exchange Commission (SEC),  including reports on the following forms: annual
report on Form 10-K,  quarterly  reports on Form 10-Q,  current  reports on Form
8-K, and  amendments  to those  reports  files or furnished  pursuant to Section
13(a) or 15(d) of the Securities Act of 1934.

                           FORWARD-LOOKING STATEMENTS

     This  prospectus  and the documents we have filed with the  Securities  and
Exchange  Commission  which we have  referenced  under  "Where You Can Find More
Information " on page [ ] contains forward- looking  statements made pursuant to
the safe harbor  provisions of the Private  Securities  Litigation Reform Act of
1995. Forward-looking statements represent our judgment regarding future events.
Although we would not make forward-looking  statements unless we believe we have
a reasonable  basis for doing so, we cannot  guarantee their accuracy and actual
results  may  differ  materially  from those we  anticipated  due to a number of
uncertainties, many of which we are not aware. We urge you to consider the risks
and  uncertainties   discussed  under  "Risk  Factors"  and  elsewhere  in  this
prospectus  and in the other  documents  filed with the Commission in evaluating
our forward-looking  statements.  We have no plans to update our forward-looking
statements to reflect events or circumstances after the date of this prospectus.
We  generally  identify  forward-looking  statements  with the words  "believe",
"intend,"  "plan,"  "expect,"  "anticipate,"  "estimate,"  "will,"  "should" and
similar expressions.

                                USE OF PROCEEDS

     This  prospectus  relates to shares of our common stock that may be offered
and sold from time to time by the selling  securityholders.  We will not receive
any of the proceeds from the sale of shares of common stock in this offering. If
the  selling  securityholders  exercise  their  warrants,  we will  receive  the
exercise price of the warrants,  which is currently $0.6936 per share. We intend
to use the net  proceeds  from the  exercise  of the  warrants  for our  general
working  capital  needs.  There can be no  assurance  that all,  or any,  of the
warrants will be exercised.

                                       10


                    RECENT SALES OF UNREGISTERED SECURITIES

     We sold the following unregistered restricted securities in reliance on the
exemptions  provided  by  Section  4(2)  and  Rule  506 of  Regulation  D of the
Securities Act as transactions not involving public offerings.

     On July 19, 2005, we entered into a Securities Purchase Agreement that will
provide us with gross  proceeds of $2.5 million  through a private  placement of
preferred stock with M.A.G.  Capital,  LLC through its designated funds: Monarch
Pointe Fund, Ltd;  Mercator  Momentum Fund, III, LP; and Mercator Momentum Fund,
LP; (the  "Investors").  The stock  purchase  agreement  provided  for a private
placement  of 25,000  shares of our Series D Preferred  Stock at $100 per share.
The preferred stock is convertible into shares of our common stock at 85 percent
of the  volume  weighted  average  price  per share  for the five  trading  days
preceding  any  conversion,  but not at more than $0.6606 or less than $0.40 per
share.  After  registering  the shares of common  stock  that could be  acquired
through  conversion of the preferred shares, we may, at our option,  require the
Investors to convert all their  preferred  stock into common stock if the market
price for the common  stock for the  preceding 20 trading days has been $1.30 or
more per  share.  Such a  conversion  by us is not  allowed if it would make the
stock held by the Investors  through this transaction and the conversion  exceed
9.99% of the common stock outstanding.  The Investors also acquired warrants for
the purchase of 1,892,219  shares of common stock. The warrants may be exercised
at a price currently of $0.6936 per share for a term of five years,  ending July
18, 2010. Under the terms of a registration rights agreement with the Investors,
we are  required  to file a  registration  statement  with  the  Securities  and
Exchange  Commission  by  September  2,  2005,  for the  shares of common  stock
underlying the preferred stock and the warrants.

     By  the  placement  of the  preferred  stock  described  above,  we  became
obligated to pay a cash dividend monthly on the outstanding  shares of preferred
stock.  The dividend rate is the higher of (i) the prime rate as reported by the
Wall Street  Journal on the first day of the month,  plus three percent or, (ii)
8.5% times $100 per share, but in no event greater than 10% annually.

     An event of default  occurs if we fail to timely pay the dividend,  fail to
timely file a registration  statement for the shares of common stock  underlying
the preferred shares and the warrants, or have not obtained effectiveness of the
registration  statement  within 90 days after its filing,  among other specified
occurrences.  Upon an event of default,  the price at which the preferred  stock
may be  converted  into common stock is reduced from 85 percent to 75 percent of
the then current volume  weighted  average market price per share,  but not more
than $0.6606 or less than $0.30 per share.  In addition,  the Investors have the
right to be paid first from our assets upon any  dissolution  or  liquidation of
the  company.  If the  registration  statement  is not timely  filed or declared
effective by the Securities and Exchange Commission,  we are required to pay the
Investors $1,467 in cash for each day of delay.

     These  securities  were  offered  and sold to the  Investors  in a  private
placement  transaction  made  in  reliance  upon  exemptions  from  registration
pursuant  to Section  4(2) of the  Securities  Act of 1933.  The  Investors  are
accredited  investors as defined in Rule 501 of Regulation D  promulgated  under
the Securities Act of 1933.

                            SELLING SECURITYHOLDERS

     This prospectus  relates to the offering and sale, from time to time, of up
to  10,787,871  shares of common  stock  issuable  upon  conversion  of Series D
Convertible  Preferred  Stock  and the  exercise  of  warrants  held by  selling
securityholders  named in the  table  below.  The  selling  securityholders  may

                                       11

convert  their  shares of Series D  Convertible  Preferred  Stock into shares of
common stock and exercise their  warrants at any time in their sole  discretion.
All of the selling  securityholders  named below  acquired  their  shares of our
Series D Convertible  Preferred  Stock and warrants  directly from us in private
transactions.

     The Series D  Convertible  Preferred  Stock is initially  convertible  into
shares of common stock at 85 percent of the volume  weighted  average  price per
share for the five trading days preceding any  conversion,  but not at more than
$0.6606  or less  than  $0.40 per  share.  At any time  after  the  registration
statement for these shares of common stock has been declared  effective,  we may
require the holders of the Series D Convertible  Preferred  Stock to convert all
their  preferred  stock into common  stock if the  closing  price for the common
stock for the  preceding  20 trading days has been greater than $1.30 per share.
The exercise  price for the  warrants to purchase  shares of our common stock is
$0.6936.  The  conversion  of  preferred  stock and  exercise of the warrants is
limited such that the beneficial  ownership of the selling  securityholders  and
their affiliates cannot exceed 9.99% of the common stock outstanding.

     The following  table sets forth certain  information  known to us as of the
date of this  prospectus  and as  adjusted  to  reflect  the sale of the  shares
offered hereby, with respect to the beneficial  ownership of common stock by the
selling  securityholders.  The number of shares of common stock set forth in the
table below assumes that each share of Series D Convertible  Preferred  Stock is
converted  into shares of our common  stock at the minimum  conversion  price of
$0.40 per share. If the selling  securityholders  convert at a higher conversion
price,  the number of shares of common  stock sold  pursuant to this  prospectus
will decrease. The selling securityholders may sell all or some of the shares of
common  stock  they  are  offering,  and may sell  shares  of our  common  stock
otherwise than pursuant to this prospectus.  The table assumes that each selling
securityholder  exercises all of its warrants and sells all of the shares issued
upon exercise  thereof,  and that each selling  securityholder  sells all of the
shares  offered by it in  offerings  pursuant  to this  prospectus,  and neither
dispose of nor acquire any  additional  shares.  We are unable to determine  the
exact number of shares that will actually be sold or when or if these sales will
occur.  None of the selling  securityholders  is an  affiliate  of a  registered
broker-dealer.



                                            Shares beneficially                              Shares beneficially
                                            owned before the                                 owned after the
                                            offering                                         offering
                                            --------                   Number of shares      --------
Name of beneficial owner                    Number     Percentage      being offered         Number    Percentage
------------------------                    ------     ----------      -----------------     ------    ----------
                                                                                             
M.A.G. Capital, LLC (1)                  8,142,219(2)  13.9%              8,142,219               0         0
Mercator Momentum Fund, LP (1)           1,940,944(3)   3.3%              1,940,944               0         0
Mercator Momentum Fund III, LP (1)       1,195,621(4)   2.0%              1,195,621               0         0
Monarch Pointe Fund, Ltd. (1)(5)         4,627,210(6)   7.9%              4,627,210               0         0
Wharton Capital Partners (7)              281,159(10)  *                    281,159               0         0
Condor Partners (8)                       140,580(11)  *                    140,580               0         0
First Equity Trust (9)                    140,580(12)  *                    140,580               0         0
----------------------------------------------------------------------------------------------------------------

The number of shares of common  stock set forth in the table above  assumes that
each share of Series D Convertible  Preferred  Stock is converted into shares of
our common stock at the minimum  conversion  price of $0.40 per share. The total
number of shares  registered  are based on a conversion  price of $.30 per share
which  would  only have  affect on an event of  default  by  Vasomedical  of its
obligation to holders of the Series D Convertible Preferred Stock. In such event
the number of shares  beneficially  owned  before the offering  would  increase,
without having any effect on the number of shares  beneficially  owned after the
offering.

(*)      Represents less than 1%

(1)  As they are affiliates,  all of the shares set forth for Mercator  Momentum
     Fund, LP, Mercator  Momentum Fund III, LP and Monarch Pointe Fund, Ltd. are
     also included in the number of shares  reflected for M.A.G.  Capital,  LLC.
     David Firestone is the Managing Member of M.A.G. Capital, LLC, which is the
     General  Partner of Mercator  Momentum Fund, LP and Mercator  Momentum Fund
     III, LP and is the Manager of Monarch Pointe Fund, Ltd. M.A.G. Capital, LLC
     holds voting and investment power over the shares held by Mercator Momentum
     Fund, LP, Mercator Momentum Fund III, LP and Monarch Pointe Fund, Ltd.
(2)  Represents  378,444 shares  issuable upon exercise of a warrant to purchase
     common  stock as well as shares  beneficially  owned by  Mercator  Momentum

                                       12


     Fund, LP,  Mercator  Momentum Fund III, LP and Monarch Pointe Fund, Ltd The
     shares of Series D preferred stock and warrants issued to Mercator Momentum
     Fund, LP,  Mercator  Momentum Fund III, LP, Monarch Pointe Fund,  Ltd., and
     M.A.G. Capital,  LLC, contain provisions  prohibiting any conversion of the
     preferred  stock or exercise  of the  warrants  that would  result in these
     entities  or their  affiliates  beneficially  owning more than 9.99% of our
     outstanding common shares as determined under Section 13(d) of the exchange
     Act. As a result of these  provisions,  such entities  disclaim  beneficial
     ownership in excess of 9.99% of our outstanding common shares.
(3)  Includes  378,444  shares  issuable  upon exercise of a warrant to purchase
     common stock and 1,562,500  shares of common stock being the maximum number
     of  shares  of  common  stock  issuable  upon  conversion  of the  Series D
     preferred stock.
(4)  Includes  233,121  shares  issuable  upon exercise of a warrant to purchase
     common stock and 962,500 shares of common stock being the maximum number of
     shares of common stock  issuable upon  conversion of the Series D preferred
     stock.
(5)  David  Firestone  is the  President of Monarch  Pointe Fund,  Ltd and holds
     voting and investment power over the shares held by Monarch Pointe.
(6)  Includes  902,210  shares  issuable  upon exercise of a warrant to purchase
     common stock and 3,725,000  shares of common stock being the maximum number
     of  shares  of  common  stock  issuable  upon  conversion  of the  Series D
     preferred stock.
(7)  Wharton Capital  Partners  acquired its shares of common stock and warrants
     as a finder's fee in connection with the Securities Purchase Agreement with
     the  investors.  Barry  Minsky is the Chief  Executive  Officer  of Wharton
     Capital  Partners and holds voting and  investment  control over the shares
     held by Wharton
(8)  Condor  Partners  acquired  its shares of common  stock and  warrants  as a
     finder's fee in connection with the Securities  Purchase Agreement with the
     investors.  Vincent  Franzone is the President of Condor Partners and holds
     voting and investment control over the shares held by Condor Partners.
(9)  First  Equity  Trust  acquired its shares of common stock and warrants as a
     finder's fee in connection with the Securities  Purchase Agreement with the
     investors.  Robert  Rover is the  President of First Equity Trust and holds
     voting and investment control over the shares held by First Equity Trust.
(10) Includes  181,159  shares  issuable  upon exercise of a warrant to purchase
     common stock.
(11) Includes  90,580  shares  issuable  upon  exercise of a warrant to purchase
     common stock.
(12) Includes  90,580  shares  issuable  upon  exercise of a warrant to purchase
     common stock.



                              PLAN OF DISTRIBUTION

     Our shares are traded on the Nasdaq  SmallCap Market under the symbol VASO.
The selling  securityholders  and any of their assignees,  pledgees,  donees and
other  successors in interest  may, from time to time,  sell any or all of their
shares on the Nasdaq SmallCap Market or in private transactions. These sales may
be at fixed or negotiated prices. The selling securityholders may use any one or
more of the following methods when selling shares:

     --   ordinary   brokerage   transactions  and  transactions  in  which  the
          broker-dealer solicits purchases;
     --   block  trades  in which the  broker-dealer  will  attempt  to sell the
          shares as agent but may  position and resell a portion of the block as
          principal to facilitate the transaction;

                                       13



     --   privately negotiated transactions;
     --   broker-dealers  may agree with the selling  securityholders  to sell a
          specified number of the shares at a stipulated price per share;
     --   a combination of any of the methods of sale listed above; and
     --   any other method permitted pursuant to applicable law.

     The selling  securityholders  may also sell shares under Rule 144 under the
Securities Act, if available, rather than under this prospectus.

     The selling  securityholders or their successors in interest may also enter
into option or other transactions with  broker-dealers that require the delivery
by the  broker-dealers of the shares,  and these shares may be resold thereafter
pursuant to this prospectus.

     Broker-dealers engaged by the selling securityholders may arrange for other
broker-dealers to participate in sales.  Broker-dealers may receive  commissions
or discounts from the selling  securityholders,  or, if a broker-dealer  acts as
agent  for the  purchaser  of  shares,  from the  purchaser,  in  amounts  to be
negotiated.  The selling  securityholders  do not expect these  commissions  and
discounts to exceed what is customary in the types of transactions involved.

     The  selling  securityholders  may  from  time to time  pledge  or  grant a
security  interest  in some or all of the shares  offered  hereby  and,  if they
default in the performance of their secured obligations, the pledgees or secured
parties may offer and sell the shares  from time to time under this  prospectus,
or  under  an  amendment  to this  prospectus  under  Rule  424(b)(3)  or  other
applicable  provision  of the  Securities  Act  amending  the  list  of  selling
securityholders  to include  the  pledgee,  transferee  or other  successors  in
interest as selling securityholders under this prospectus.

     The  selling  securityholders  may also  transfer  the shares  under  other
circumstances,  in which case the  transferees,  pledgees or other successors in
interest will be the selling beneficial owners for purposes of this prospectus.

     Brokers, dealers,  underwriters or agents participating in the distribution
of the shares as agents may  receive  compensation  in the form of  commissions,
discounts or concessions from the selling  securityholders  and/or purchasers of
the shares for whom such  broker-dealers  may act as agent,  or to whom they may
sell as principal, or both, which compensation as to a particular  broker-dealer
may be less than or in excess of customary commissions.

     The  selling  securityholders  and any  broker-dealers  or agents  that are
involved  in selling  the shares may be deemed to be  "underwriters"  within the
meaning of the Securities Act in connection with such sales. In such event,  any
commissions  received  by such  broker-dealers  or agents  and any profit on the
resale  of the  shares  purchased  by  them  may be  deemed  to be  underwriting
commissions or discounts under the Securities Act.

     Each of the selling  securityholders  has informed us that it does not have
any  agreement  or  understanding,  directly or  indirectly,  with any person to
distribute the shares.  If any selling  shareholder  notifies us that a material

                                       14


arrangement  has been entered into with a  broker-dealer  for the sale of shares
through a block trade, special offering, secondary distribution or a purchase by
a broker or dealer, we will file a prospectus  supplement,  if required pursuant
to Rule 424(c) under the Securities Act, setting forth:

     --   the name of each of the participating broker-dealers;
     --   the number of shares involved;
     --   the price at which the shares were sold;
     --   the  commissions  paid or  discounts  or  concessions  allowed  to the
          broker-dealers, where applicable;
     --   a statement to the effect that the  broker-dealers did not conduct any
          investigation  to verify the  information  set out or  incorporated by
          reference in this prospectus; and
     --   any other facts material to the transaction.

     We are required to pay all fees and expenses  incident to the  registration
of the shares  being  offered by the  selling  securityholders  pursuant to this
prospectus.  We have agreed to  indemnify  the selling  securityholders  against
certain losses, claims, damages and liabilities, including liabilities under the
Securities Act.

     We have advised the selling  securityholders  that during the time they may
be engaged in a distribution of the shares offered by this prospectus,  they are
required to comply with Regulation M promulgated  under the Securities  Exchange
Act  of  1934,  as  amended  (the  "Exchange  Act").  With  certain  exceptions,
Regulation M precludes any selling  securityholders,  any affiliated  purchasers
and any broker- dealer or other person who participates in the distribution from
bidding  for or  purchasing,  or  attempting  to induce any person to bid for or
purchase any security which is the subject of the distribution  until the entire
distribution is complete. Regulation M also prohibits any bids or purchases made
in order to  stabilize  the price of a  security  in  connection  with an at the
market  offering  such as this  offering.  All of the  foregoing  may affect the
marketability of the shares.

                         DESCRIPTION OF OUR SECURITIES

Capital Stock

     Our  authorized  capital  stock  consists of  110,000,000  shares of common
stock,  par value $.001 per share and 1,000,000  shares of Preferred  Stock, par
value $.01 per share.

Common Stock

     General. We have 110,000,000  authorized shares of common stock. All of our
shares  of  common  stock  outstanding  are  validly  issued,   fully  paid  and
non-assessable.

     Voting Rights.  Each share of common stock entitles its holder to one vote,
either  in  person  or by  proxy,  at  meetings  of  stockholders.  Our board of
directors  consists of three  classes  each of which  serves for a term of three
years.  At each annual  meeting of the  stockholders,  the directors in only one

                                       15


class will be  elected.  The  holders  are not  permitted  to vote their  shares
cumulatively.  Accordingly,  the holders of more than fifty percent (50%) of the
issued and outstanding shares of common stock can elect all of our directors.

     Dividend  Policy.  All shares of common stock are  entitled to  participate
ratably in dividends  when and as declared by our board of directors  out of the
funds legally  available for payment of dividends.  Any dividends may be paid in
cash,  property or additional  shares of common stock. We presently  expect that
any earnings will be used to develop our business and that no cash  dividends on
the shares of common stock will be declared in the foreseeable future.

     Miscellaneous Rights and Provisions. Holders of common stock do not have:

--       preemptive or other subscription rights;
--       conversion rights;
--       redemption; or
--       sinking fund provisions.

     In the  event of our  liquidation  or  dissolution,  whether  voluntary  or
involuntary,  each share of common  stock is  entitled  to share  ratably in any
assets  available  for  distribution  to  our  holders  of  common  stock  after
satisfaction of all liabilities,  including payments to holders of our preferred
stock.

Undesignated Preferred Stock

     We are  authorized to issue  1,000,000  shares of preferred  stock of which
25,000 shares have been  designated at Series D Convertible  Preferred Stock and
are currently  issued and  outstanding.  Our board of directors is authorized to
issue  from  time to time,  without  stockholder  authorization,  in one or more
designated  series or classes,  any or all of the authorized but unissued shares
of  preferred  stock with such  dividend  redemption,  conversion  and  exchange
provisions as may be provided in the particular  series. Any series of preferred
stock may possess voting,  dividend,  liquidation and redemption rights superior
to that of the common  stock.  The rights of the holders of common stock will be
subject to and may be  adversely  affected  by the rights of the  holders of any
preferred  stock that may be issued in the  future.  Issuance of a new series of
preferred  stock,  while  providing  desirable  flexibility  in connection  with
possible acquisition and other corporate purposes,  could make it more difficult
for a third  party to acquire or  discourage  a third  party from  acquiring,  a
majority of the outstanding voting power of Vasomedical.

Series D Convertible Preferred Stock

     There are 25,000 shares of Series D Convertible  Preferred  Stock currently
issued and outstanding.

     Conversion

     The Series D  Convertible  Preferred  Stock is  convertible  into shares of
common stock at 85 percent of the volume  weighted  average  price per share for
the five trading days preceding any conversion,  but not at more than $0.6606 or
less than $0.40 per share. After the shares have been registered, we may require
the holders to convert all of their  preferred  stock for shares of common stock
if the price for the common  stock for the  preceding  20 trading  days has been
$1.30 or more per share.

                                       16

     Dividends

     Dividends  are  payable  monthly  in  cash  on the  outstanding  shares  of
preferred  stock.  The  dividend  rate is the  higher of (i) the  prime  rate as
reported  by the Wall Street  Journal on the first day of the month,  plus three
percent, or (ii) 8.5% times $100 per share, but in no event greater than 10%.

     Events of Default

     An event of default occurs if Vasomedical fails to timely pay the dividend,
fails to timely file a  registration  statement  for the shares of common  stock
underlying  the  preferred  shares  and  the  warrants,   or  has  not  obtained
effectiveness  of the  registration  statement by December 1, 2005,  among other
specified  occurrences.  Upon an  event of  default,  the  price  at  which  the
preferred stock may be converted into common stock is reduced from 85 percent to
75 percent of the then current volume  weighted  average market price per share,
but not more than $0.6606 or less than $0.30 per share.

     Liquidation Preference

     The holders of the preferred stock have the right to be paid first from the
assets of Vasomedical upon any dissolution or liquidation of Vasomedical.

                                 LEGAL MATTERS

     Certain legal matters in connection  with this offering will be passed upon
for the Company by Beckman, Lieberman & Barandes,LLP, Jericho, New York 11753.

                                    EXPERTS

     The financial  statements  incorporated by reference in this prospectus and
elsewhere in the registration statement have been audited by Grant Thornton LLP,
independent registered public accounting firm, as set forth in their report. The
financial  statements  referred to above have been  included  herein in reliance
upon the authority incorporated by reference of those forms as experts in giving
said report.

    DISCLOSURE OF COMMISSION POSITION ON INDEMNIFICATION FOR SECURITIES ACT
                                  LIABILITIES

     Our By-Laws  provide our directors  with  protection  for breaches of their
fiduciary  duties to us and our  stockholders.  Insofar as  indemnification  for
liabilities  arising under the Securities Act may be permitted to our directors,
officers or persons  controlling  us, we have been  advised that it is the SEC's
opinion that such  indemnification  is against public policy as expressed in the
Securities Act and is, therefore, unenforceable.

                      WHERE YOU CAN FIND MORE INFORMATION

     We file annual,  quarterly and current reports,  proxy statements and other
information  with the SEC.  You may read and copy any  document we file with the
SEC at the SEC's Public  Reference  Room at 450 Fifth  Street,  NW,  Washington,
D.C., 20549.  Please call the SEC at 1-800-SEC-0330  for further  information on
the operation of the Public  Reference Rooms. Our SEC filings are also available
to the public on the SEC's Website at "http://www.sec.gov."

     We have filed with the SEC a  registration  statement on Form S-3 under the
Securities  Act of 1933,  as amended,  with  respect to the shares to be sold in

                                       17


this offering. This prospectus does not contain all of the information set forth
in the registration statement. We have omitted certain parts of the registration
statement in accordance  with the rules and  regulations of the SEC. For further
information  about us and the  shares,  you  should  refer  to the  registration
statement.  Statements  contained in this  prospectus  as to the contents of any
contract or other document are not  necessarily  complete and, in each instance,
you should refer to the copy of such contract or document filed as an exhibit to
or incorporated by reference in the registration statement. Each statement as to
the  contents of such  contract or document is qualified in all respects by such
reference.  You may obtain a copy of the registration  statement,  or any of our
other filings with the SEC, from the SEC's principal office in Washington,  D.C.
upon payment of the fees prescribed by the SEC.

                INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

     The SEC allows us to  "incorporate  by reference"  the  information we file
with them,  which means that we can  disclose  important  information  to you by
referring you to those documents.  The information  incorporated by reference is
considered to be part of this  prospectus,  and  information  that we file later
with the SEC will  automatically  update  and  supersede  this  information.  We
incorporate  by reference the documents  listed below and any future  filings we
will  make  with  the SEC  under  Sections  13(a),  13(c),  14 or  15(d)  of the
Securities Exchange Act of 1934. The documents we are incorporating by reference
are:

     --   Our annual report on Form 10-K for our fiscal year ended May 31, 2005;

     --   Our current report on Form 8-K filed July 22, 2005.

     You may  request  a copy  of  these  filings  at no  cost,  by  writing  or
telephoning our secretary at the following address:

                        Vasomedical, Inc.
                        180 Linden Avenue
                        Westbury, New York  11590
                        (516) 997-4600

                                       18