Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0104
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
  NEW ENTERPRISE ASSOCIATES 11 LP
2. Date of Event Requiring Statement (Month/Day/Year)
05/30/2007
3. Issuer Name and Ticker or Trading Symbol
AMICUS THERAPEUTICS INC [FOLD]
(Last)
(First)
(Middle)
1119 ST. PAUL STREET
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

BALTIMORE, MD 21202
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Series B Convertible Preferred Stock   (1)   (2) Common Stock 990,796 $ (3) D (4)  
Series C Convertible Preferred Stock   (1)   (2) Common Stock 1,016,220 $ (3) D (4)  
Series D Convertible Preferred Stock   (1)   (2) Common Stock 1,634,473 $ (3) D (4)  
Series B Convertible Preferred Stock Warrant (Right to Buy) 05/04/2004 05/04/2014 Series B Convertible Preferred Stock 15,077 $ 6.375 D (4)  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
NEW ENTERPRISE ASSOCIATES 11 LP
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
NEA PARTNERS 11 LP
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
NEA 11 GP, LLC
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
BARRETT M JAMES
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
BASKETT FOREST
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
DRANT RYAN D
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
LINEHAN CHARLES M
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
SANDELL SCOTT D
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
TRAINOR III EUGENE A
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
KOLLURI KRISHNA KITTU
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    

Signatures

/s/ Shawn Conway, attorney-in-fact 05/30/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Convertible at any time.
(2) Not applicable.
(3) Each share of Preferred Stock will automatically convert into one (1) share of Common Stock upon the closing of the Issuer's initial public offering.
(4) The securities are directly held by New Enterprise Associates 11, Limited Partnership ("NEA 11") and indirectly held by NEA Partners 11, Limited Partnership ("NEA Partners 11"), the sole general partner of NEA 11, NEA 11 GP, LLC ("NEA GP"), the sole general partner of NEA Partners 11, and the individual managers of NEA GP (NEA Partners 11, NEA GP and the individual managers of NEA GP together, the "Indirect Reporting Person"). The individual managers of NEA GP are M. James Barrett, Peter J. Barris, Forest Baskett, Ryan D. Drant, Krishna "Kittu" Kolluri, C. Richard Kramlich, Charles M. Linehan, Charles W. Newhall III, Mark W. Perry, Scott D. Sandell and Eugene A. Trainor III. Each Indirect Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 11 shares in which such Indirect Reporting Person has no actual pecuniary interest therein.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.