UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington D.C., 20549

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                                    Form 8-K

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                                 Current Report
     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

          Date Of Report (Date Of Earliest Event Reported): 8/25/2010

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                               PURESPECTRUM, INC.
             (Exact Name of Registrant as Specified in its Charter)

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                       Commission File Number: 333-148158

            Delaware                                      41-2233202
(State or Other Jurisdiction Of                        (I.R.S. Employer
 Incorporation or Organization)                       Identification No.)

                               340 Eisenhower Dr.
                            Building 600, Suite 610
                            Savannah, Georgia 31406
          (Address of Principal Executive Offices, Including Zip Code)

                                  912-961-4980
              (Registrant's Telephone Number, Including Area Code)

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Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:

[ ]  Written communications pursuant to Rule 425 under the Securities Act (17
     CFR 230.425)

[ ]  Soliciting material pursuant to Rule 14a-12 under the Exchange Act
     (17CFR240.14a-12)

[ ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the
     Exchange Act(17CFR240.14d-2(b))

[ ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the
     Exchange Act(17CFR240.13e-4(c))


Item 5.02.   Departure of Directors or Certain Officers; Election of Directors;
Appointment of Certain Officers; Compensatory of Certain Officers.

Effective August 25, 2010, the Directors of the Company, by a majority vote
constituting a majority of the Directors of the Company, accepted the
resignation of Chairman and Chief Executive Officer Lee L. Vanatta effective
immediately.

Regarding  the  circumstances  surrounding  the  acceptance  of  Mr.  Vanatta's
resignation,  in  March  2010,  the registrant's former Chief Financial Officer,
Gregory  G.  McLean,  made  allegations  in  a  letter  of  resignation that the
Directors  believed  merited investigation. Mr. Thomas J. Bellante, a partner in
the  auditing firm of Pender Newkirk & Company located in Jacksonville, Florida,
confirmed in a telephone conference with the registrant's acting Audit Committee
chairman  William  G. Garlen the need to thoroughly investigate the allegations.
Subsequent  to  Mr.  McLean's  allegations, another former insider and a current
shareholder, Tony Golden, made other serious allegations and publicly called for
the  registrant's  Board  of Directors to take action. The Directors immediately
launched  an  investigation  pertaining  to  company  activities  and  sought
information from management regarding the substance of the allegations raised by
Messrs.  McLean  and  Golden.

Due  to the seriousness of the allegations and the need for confidentiality, the
Directors  did  not feel it appropriate to directly contact either Mr. Golden or
Mr.  Mclean but believed that both individuals were acting as whistleblowers and
had  insider  information not available to the Directors that was detrimental to
shareholder  value  and  company  equity.

The Directors, collectively and in their respective capacities as the Audit
Committee, Compensation Committee and outside legal counsel have continued to
relentlessly pursue this investigation during the past four months. On August
19, 2010 the Directors made certain demands on the company's management to
comply with full and complete disclosure. The Directors have unanimously reached
the following conclusions regarding management:

-     Management has continually failed to fully and truthfully comply with the
      Board's requests for information regarding the company's sales, revenue,
      payables or tax compliance;

-     Management has failed to fully disclose the company's financial condition;

-     Management has repeatedly obligated the company to contracts, including
      leases, promissory notes and other obligations, knowing that the company
      has no ability to pay and without the prior knowledge or consent of the
      Board of Directors;

The Directors judge these actions by management to be malfeasance of duty and
willful misconduct on behalf of management. Furthermore, the Directors find that
management's repeated failure to deliver on any revenue or sales projections
presented to the Board of Directors and refusal to engage in any significant
cost-cutting measures to be gross and negligent mismanagement of company, and
therefore, shareholder assets.

PureSpectrum is an insolvent company. It is likely that the Company will not
continue operations. The Directors will use their best efforts to identify
potential investors who might inject capital into the company in order to
preserve some value for the company's shareholders and seek management that will
cooperate promptly, fully and truthfully with any request for information made
by such investors. There is no guarantee, however, that any such efforts will be
successful.

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                                  Signature(s)

     Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this Report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                      PureSpectrum, Inc.

Date: August 25, 2010                 By:  /S/ Gregory K. Clements
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                                           Name: Gregory K. Clements
                                           Title: Chief Financial Officer

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