UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  FORM 12b-25

                          NOTIFICATION OF LATE FILING

                                                      SEC File Number 333-148158

                                                      CUSIP NUMBER: 74624D102000

          (Check One): [  ] Form 10-K   [_] Form 20-F   [_] Form 11-K
                [X] Form 10-Q   [_] Form N-SAR   [_] Form N-CSR

For Period Ended: March 31, 2010
                  --------------
[ ] Transition Report on Form 10-K
[ ] Transition Report on Form 20-F
[ ] Transition Report on Form 11-K
[ ] Transition Report on From 10-Q
[ ] Transition Report on Form N-SAR
For the Transition Period Ended: _____________

  Read attached instruction sheet before preparing form. Please print or type.

     Nothing in this form shall be construed to imply that the Commission has
verified any information contained herein.

     If  the  notification  relates  to  a  portion of the filing checked above,
identify  the  item(s)  to  which  the  notification  relates:__________________

PART I - REGISTRANT INFORMATION

Full name of registrant:

                               PURESPECTRUM, INC.
Former name if applicable:

                      INTERNATIONAL MEDICAL STAFFING, INC.
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Address of principal executive office (Street and number):

                              340 Eisenhower Drive
                            Building 600, Suite 610
                            Savannah, Georgia 31406

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PART II - RULE 12b-25 (b) AND (c)

     If the subject report could not be filed without unreasonable effort or
expense and the registrant seeks relief pursuant to Rule 12b-25(b), the
following should be completed. (Check box if appropriate.) [X]

(a) The  reasons  described  in reasonable detail in Part III of this form could
    not be eliminated without unreasonable effort or expense;

(b) The subject  annual  report,   semi-annual report, transition report on Form
    10-K,  Form  20-F,  Form 11-K,  Form N-SAR or Form N-CSR, or portion thereof
    will  be  filed  on  or  before  the  fifteenth  calendar  day following the
    prescribed  due  date;  or the subject quarterly report or transition report
    on Form 10-Q, or portion thereof  will  be  filed  on  or  before the  fifth
    calendar  day  following  the prescribed  due  date;  and

(c) The  accountant's  statement or other exhibit required by Rule 12b-25(c) has
    been  attached  if  applicable.

PART III - NARRATIVE

     State below in reasonable detail why Forms 10-K, 20-F, 10-Q, N-SAR or N-CSR
or  the  transition  report  portion  thereof,  could  not  be  filed within the
prescribed  time  period.  (Attach  extra  sheets  if  needed.)

     The registrant acted as the acquiring entity in an acquisition, in November
2009,  of  an operating company.  The accounting staff has been heavily involved
in combining the books and operating results of the two companies.  As a result,
the  subject  report  could not be filed without unreasonable effort or expense.

PART IV - OTHER INFORMATION

     (1)     Name  and  telephone  number of person to contact in regard to this
notification:

Lee L. Vanatta
--------------
(Name)

(912)         961-4980
--------------------------
(Area Code) (Telephone Number)

     (2)     Have  all other periodic reports required under Section 13 of 15(d)
of  the  Securities Exchange Act of 1934 or Section 30 of the Investment Company
Act  of  1940 during the preceding 12 months or for such shorter period that the
registrant  was required to file such report(s) been filed? If the answer is no,
identify  report(s).

                                 [X] Yes [ ] No

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     (3)     Is  it  anticipated  that  any  significant  change  in  results of
operations  from  the  corresponding  period  for  the  last fiscal year will be
reflected  by  the  earnings  statements to be included in the subject report or
portion  thereof?

                                 [X] Yes [_] No

     If  so,  attach  an explanation of the anticipated change, both narratively
and  quantitatively  and,  if  appropriate,  state  the reasons why a reasonable
estimate  of  the  results  cannot  be  made.

     The  registrant  will  report  an  approximately  $2.3  million  loss  from
operations  compared to a $1.3 million loss for the quarter ended March 31, 2010
incurred  by  PureSpectrum, Inc., a Nevada corporation ("PSPM").  The registrant
acquired PSPM in November 2009 in a transaction treated for financial accounting
purposes  as  a  reverse  acquisition.

                               PURESPECTRUM, INC.
                               ------------------
                  (Name of Registrant as Specified in Charter)

Has caused this notification to be signed on its behalf by the undersigned
thereunto duly authorized.

Date:  May 11, 2010

                                      By:  /S/ Lee L. Vanatta
                                           ------------------
                                           Lee L. Vanatta,
                                           President and Chief Executive Officer

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