UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13G
                                (Rule 13d - 102)

                    Under the Securities Exchange Act of 1934



                    BIODELIVERY SCIENCES INTERNATIONAL, INC.
--------------------------------------------------------------------------------
                                (Name of Issuer)

                    Common Stock, par value $0.001 per share
--------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    09060J106
--------------------------------------------------------------------------------
                                 (CUSIP Number)

                                December 29, 2006
--------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

Check the  appropriate box to designate the rule pursuant to which this Schedule
13G is filed:

         |_|  Rule 13d-1(b)
         |X|  Rule 13d-1(c)
         |_|  Rule 13d-1(d)

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).




--------------------------------------------------------------------------------

CUSIP No. 47008R103
--------------------------------------------------------------------------------
1    NAME OF REPORTING PERSON: Laurus Master Fund, Ltd.
     S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON: 98-0337673

--------------------------------------------------------------------------------
2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
     (a)  |_|
     (b)  |_|
--------------------------------------------------------------------------------
3    SEC USE ONLY


--------------------------------------------------------------------------------
4    CITIZENSHIP OR PLACE OF ORGANIZATION

     Cayman Islands
--------------------------------------------------------------------------------
               5    SOLE VOTING POWER

                    0 shares of Common Stock.*
               -----------------------------------------------------------------
  NUMBER OF    6    SHARED VOTING POWER
   SHARES
BENEFICIALLY        1,392,420 shares of Common Stock.*
  OWNED BY     -----------------------------------------------------------------
    EACH       7    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON           0 shares of Common Stock.*
    WITH       -----------------------------------------------------------------
               8    SHARED DISPOSITIVE POWER

                    1,392,420 shares of Common Stock.*
--------------------------------------------------------------------------------
9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     1,392,420 shares of Common Stock.
--------------------------------------------------------------------------------
10   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
                                                                             |X|

--------------------------------------------------------------------------------
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     9.99%*
--------------------------------------------------------------------------------
12   TYPE OF REPORTING PERSON

     CO
--------------------------------------------------------------------------------

----------------------------

         * Based on 13,938,146  shares of the common stock, par value $0.001 per
share (the "Shares") of  BioDelivery  Sciences  International,  Inc., a Delaware
corporation  (the  "Company")  outstanding,  as  represented  in  the  Company's
Quarterly  Report on Form 10-QSB for the period ended  September 30, 2006. As of
December 29, 2006, Laurus Master Fund, Ltd. (the "Fund") held (i) a common stock
purchase  warrant  (the  "January  Warrant #1") to acquire  22,500  Shares at an
exercise price of $0.01 per share, subject to certain adjustments, (ii) a common
stock purchase warrant (the "January Warrant #2") to acquire 39,574 Shares at an
exercise  price of $.01,  subject to certain  adjustments,  (iii) a common stock
purchase  warrant  (the  "January  Warrant #3") to acquire  29,700  Shares at an
exercise  price of $.01,  subject to certain  adjustments;  (iv) a common  stock
purchase  warrant (the  "January  Warrant #4") to acquire  350,000  Shares at an
exercise  price of $3.00,  subject to certain  adjustments,  (v) a common  stock
purchase  warrant (the  "January  Warrant #5") to acquire  483,871  Shares at an
exercise  price of $3.88,  subject to certain  adjustments,  (vi) a common stock
purchase warrant (the "July Warrant #1") to acquire 47,113 Shares at an exercise
price of $3.00,  subject to certain  adjustments;  (vii) a common stock purchase
warrant  (the "July  Warrant #2" and together  with the January  Warrant #1, the
January  Warrant #2, the January Warrant #3, the January Warrant #4, the January
Warrant #5 and the July  Warrant #1, the "Early  Warrants")  to acquire  110,000
Shares, at an exercise price of $3.88, subject to certain adjustments,  (viii) a
common stock  purchase  Warrant (the "December  Warrant #1") to acquire  943,305
Shares, at an exercise price of $3.05, subject to certain  adjustments,  (vii) a
common stock purchase  warrant (the "December  Warrant #2" and together with the
December Warrant #1, the "December  Warrants") to acquire 556,695 Shares,  at an
exercise  price of $3.05 per share,  subject to  certain  adjustments,  (viii) a
Convertible Term Note in the aggregate principal amount of $2,500,000, a portion
of which is convertible  into Shares at a conversion  rate of $2.45,  subject to
certain  adjustments  ("Note #1"); (ix) a Convertible Term Note in the aggregate
principal amount of $2,500,000, a portion of which is convertible into Shares at
a  conversion  rate of $2.45,  subject to certain  adjustments  ("Note #2",  and
together with Note #1, the "Notes");  and (x) 19,403 Shares.  The Early Warrants
and  the  Notes  contain  an  issuance  limitation  prohibiting  the  Fund  from
exercising  those  securities to the extent that such  exercise  would result in
beneficial  ownership  by the Fund of more than 4.99% of the Shares  then issued
and outstanding (the "4.99% Issuance Limitation"). The December Warrants contain
an issuance limitation  prohibiting the Fund from exercising those securities to
the extent that such exercise  would result in beneficial  ownership by the Fund
of more than  9.99% of the  Shares  then  issued  and  outstanding  (the  "9.99%
Issuance  Limitation"  and  together  with the 4.99%  Issuance  Limitation,  the
"Issuance Limitations"). The Issuance Limitations may be waived by the Fund upon
75 days prior notice to the Company and shall automatically become null and void
following notice to the Issuer of the occurrence and/or  continuance of an Event
of  Default  (as  defined  in and  pursuant  to  the  terms  of  the  applicable
instrument).  The Fund is managed by Laurus Capital Management, LLC. Eugene Grin
and David Grin, through other entities, are the controlling principals of Laurus
Capital  Management,  LLC and share sole  voting and  investment  power over the
securities owned by the Fund reported in this Schedule 13G, as amended.


--------------------------------------------------------------------------------

CUSIP No. 47008R103
--------------------------------------------------------------------------------
1    NAME OF REPORTING PERSON: Laurus Capital Management, LLC
     S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON:  13-4150669

--------------------------------------------------------------------------------
2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
     (a)  |_|
     (b)  |_|
--------------------------------------------------------------------------------
3    SEC USE ONLY


--------------------------------------------------------------------------------
4    CITIZENSHIP OR PLACE OF ORGANIZATION

     Delaware
--------------------------------------------------------------------------------
               5    SOLE VOTING POWER

                    0 shares of Common Stock.*
               -----------------------------------------------------------------
  NUMBER OF    6    SHARED VOTING POWER
   SHARES
BENEFICIALLY        1,392,420 shares of Common Stock.*
  OWNED BY     -----------------------------------------------------------------
    EACH       7    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON           0 shares of Common Stock.*
    WITH       -----------------------------------------------------------------
               8    SHARED DISPOSITIVE POWER

                    1,392,420 shares of Common Stock.*
--------------------------------------------------------------------------------
9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     1,392,420 shares of Common Stock.
--------------------------------------------------------------------------------
10   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
                                                                             |X|

--------------------------------------------------------------------------------
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     9.99%
--------------------------------------------------------------------------------
12   TYPE OF REPORTING PERSON

     OO
--------------------------------------------------------------------------------

----------------------------
         * Based on 13,938,146  shares of the common stock, par value $0.001 per
share (the "Shares") of  BioDelivery  Sciences  International,  Inc., a Delaware
corporation  (the  "Company")  outstanding,  as  represented  in  the  Company's
Quarterly  Report on Form 10-QSB for the period ended  September 30, 2006. As of
December 29, 2006, Laurus Master Fund, Ltd. (the "Fund") held (i) a common stock
purchase  warrant  (the  "January  Warrant #1") to acquire  22,500  Shares at an
exercise price of $0.01 per share, subject to certain adjustments, (ii) a common
stock purchase warrant (the "January Warrant #2") to acquire 39,574 Shares at an
exercise  price of $.01,  subject to certain  adjustments,  (iii) a common stock
purchase  warrant  (the  "January  Warrant #3") to acquire  29,700  Shares at an
exercise  price of $.01,  subject to certain  adjustments;  (iv) a common  stock
purchase  warrant (the  "January  Warrant #4") to acquire  350,000  Shares at an
exercise  price of $3.00,  subject to certain  adjustments,  (v) a common  stock
purchase  warrant (the  "January  Warrant #5") to acquire  483,871  Shares at an
exercise  price of $3.88,  subject to certain  adjustments,  (vi) a common stock
purchase warrant (the "July Warrant #1") to acquire 47,113 Shares at an exercise
price of $3.00,  subject to certain  adjustments;  (vii) a common stock purchase
warrant  (the "July  Warrant #2" and together  with the January  Warrant #1, the
January  Warrant #2, the January Warrant #3, the January Warrant #4, the January
Warrant #5 and the July  Warrant #1, the "Early  Warrants")  to acquire  110,000
Shares, at an exercise price of $3.88, subject to certain adjustments,  (viii) a
common stock  purchase  Warrant (the "December  Warrant #1") to acquire  943,305
Shares, at an exercise price of $3.05, subject to certain  adjustments,  (vii) a
common stock purchase  warrant (the "December  Warrant #2" and together with the
December Warrant #1, the "December  Warrants") to acquire 556,695 Shares,  at an
exercise  price of $3.05 per share,  subject to  certain  adjustments,  (viii) a
Convertible Term Note in the aggregate principal amount of $2,500,000, a portion
of which is convertible  into Shares at a conversion  rate of $2.45,  subject to
certain  adjustments  ("Note #1"); (ix) a Convertible Term Note in the aggregate
principal amount of $2,500,000, a portion of which is convertible into Shares at
a  conversion  rate of $2.45,  subject to certain  adjustments  ("Note #2",  and
together with Note #1, the "Notes");  and (x) 19,403 Shares.  The Early Warrants
and  the  Notes  contain  an  issuance  limitation  prohibiting  the  Fund  from
exercising  those  securities to the extent that such  exercise  would result in
beneficial  ownership  by the Fund of more than 4.99% of the Shares  then issued
and outstanding (the "4.99% Issuance Limitation"). The December Warrants contain
an issuance limitation  prohibiting the Fund from exercising those securities to
the extent that such exercise  would result in beneficial  ownership by the Fund
of more than  9.99% of the  Shares  then  issued  and  outstanding  (the  "9.99%
Issuance  Limitation"  and  together  with the 4.99%  Issuance  Limitation,  the
"Issuance Limitations"). The Issuance Limitations may be waived by the Fund upon
75 days prior notice to the Company and shall automatically become null and void
following notice to the Issuer of the occurrence and/or  continuance of an Event
of  Default  (as  defined  in and  pursuant  to  the  terms  of  the  applicable
instrument).  The Fund is managed by Laurus Capital Management, LLC. Eugene Grin
and David Grin, through other entities, are the controlling principals of Laurus
Capital  Management,  LLC and share sole  voting and  investment  power over the
securities owned by the Fund reported in this Schedule 13G, as amended.



--------------------------------------------------------------------------------

CUSIP No. 47008R103
--------------------------------------------------------------------------------
1    NAME OF REPORTING PERSON: David Grin

--------------------------------------------------------------------------------
2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
     (a)  |_|
     (b)  |_|
--------------------------------------------------------------------------------
3    SEC USE ONLY


--------------------------------------------------------------------------------
4    CITIZENSHIP OR PLACE OF ORGANIZATION

     Israel
--------------------------------------------------------------------------------
               5    SOLE VOTING POWER

                    0 shares of Common Stock.*
               -----------------------------------------------------------------
  NUMBER OF    6    SHARED VOTING POWER
   SHARES
BENEFICIALLY        1,392,420 shares of Common Stock.*
  OWNED BY     -----------------------------------------------------------------
    EACH       7    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON           0 shares of Common Stock.*
    WITH       -----------------------------------------------------------------
               8    SHARED DISPOSITIVE POWER

                    1,392,420 shares of Common Stock.*
--------------------------------------------------------------------------------
9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     1,392,420 shares of Common Stock.
--------------------------------------------------------------------------------
10   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
                                                                             |X|

--------------------------------------------------------------------------------
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     9.99%
--------------------------------------------------------------------------------
12   TYPE OF REPORTING PERSON

     IN
--------------------------------------------------------------------------------

----------------------------
         * Based on 13,938,146  shares of the common stock, par value $0.001 per
share (the "Shares") of  BioDelivery  Sciences  International,  Inc., a Delaware
corporation  (the  "Company")  outstanding,  as  represented  in  the  Company's
Quarterly  Report on Form 10-QSB for the period ended  September 30, 2006. As of
December 29, 2006, Laurus Master Fund, Ltd. (the "Fund") held (i) a common stock
purchase  warrant  (the  "January  Warrant #1") to acquire  22,500  Shares at an
exercise price of $0.01 per share, subject to certain adjustments, (ii) a common
stock purchase warrant (the "January Warrant #2") to acquire 39,574 Shares at an
exercise  price of $.01,  subject to certain  adjustments,  (iii) a common stock
purchase  warrant  (the  "January  Warrant #3") to acquire  29,700  Shares at an
exercise  price of $.01,  subject to certain  adjustments;  (iv) a common  stock
purchase  warrant (the  "January  Warrant #4") to acquire  350,000  Shares at an
exercise  price of $3.00,  subject to certain  adjustments,  (v) a common  stock
purchase  warrant (the  "January  Warrant #5") to acquire  483,871  Shares at an
exercise  price of $3.88,  subject to certain  adjustments,  (vi) a common stock
purchase warrant (the "July Warrant #1") to acquire 47,113 Shares at an exercise
price of $3.00,  subject to certain  adjustments;  (vii) a common stock purchase
warrant  (the "July  Warrant #2" and together  with the January  Warrant #1, the
January  Warrant #2, the January Warrant #3, the January Warrant #4, the January
Warrant #5 and the July  Warrant #1, the "Early  Warrants")  to acquire  110,000
Shares, at an exercise price of $3.88, subject to certain adjustments,  (viii) a
common stock  purchase  Warrant (the "December  Warrant #1") to acquire  943,305
Shares, at an exercise price of $3.05, subject to certain  adjustments,  (vii) a
common stock purchase  warrant (the "December  Warrant #2" and together with the
December Warrant #1, the "December  Warrants") to acquire 556,695 Shares,  at an
exercise  price of $3.05 per share,  subject to  certain  adjustments,  (viii) a
Convertible Term Note in the aggregate principal amount of $2,500,000, a portion
of which is convertible  into Shares at a conversion  rate of $2.45,  subject to
certain  adjustments  ("Note #1"); (ix) a Convertible Term Note in the aggregate
principal amount of $2,500,000, a portion of which is convertible into Shares at
a  conversion  rate of $2.45,  subject to certain  adjustments  ("Note #2",  and
together with Note #1, the "Notes");  and (x) 19,403 Shares.  The Early Warrants
and  the  Notes  contain  an  issuance  limitation  prohibiting  the  Fund  from
exercising  those  securities to the extent that such  exercise  would result in
beneficial  ownership  by the Fund of more than 4.99% of the Shares  then issued
and outstanding (the "4.99% Issuance Limitation"). The December Warrants contain
an issuance limitation  prohibiting the Fund from exercising those securities to
the extent that such exercise  would result in beneficial  ownership by the Fund
of more than  9.99% of the  Shares  then  issued  and  outstanding  (the  "9.99%
Issuance  Limitation"  and  together  with the 4.99%  Issuance  Limitation,  the
"Issuance Limitations"). The Issuance Limitations may be waived by the Fund upon
75 days prior notice to the Company and shall automatically become null and void
following notice to the Issuer of the occurrence and/or  continuance of an Event
of  Default  (as  defined  in and  pursuant  to  the  terms  of  the  applicable
instrument).  The Fund is managed by Laurus Capital Management, LLC. Eugene Grin
and David Grin, through other entities, are the controlling principals of Laurus
Capital  Management,  LLC and share sole  voting and  investment  power over the
securities owned by the Fund reported in this Schedule 13G, as amended.



--------------------------------------------------------------------------------

CUSIP No. 47008R103
--------------------------------------------------------------------------------
1    NAME OF REPORTING PERSON: Eugene Grin

--------------------------------------------------------------------------------
2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
     (a)  |_|
     (b)  |_|
--------------------------------------------------------------------------------
3    SEC USE ONLY


--------------------------------------------------------------------------------
4    CITIZENSHIP OR PLACE OF ORGANIZATION

     United States
--------------------------------------------------------------------------------
               5    SOLE VOTING POWER

                    0 shares of Common Stock.*
               -----------------------------------------------------------------
  NUMBER OF    6    SHARED VOTING POWER
   SHARES
BENEFICIALLY        1,392,420 shares of Common Stock.*
  OWNED BY     -----------------------------------------------------------------
    EACH       7    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON           0 shares of Common Stock.*
    WITH       -----------------------------------------------------------------
               8    SHARED DISPOSITIVE POWER

                    1,392,420 shares of Common Stock.*
--------------------------------------------------------------------------------
9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     1,392,420 shares of Common Stock.
--------------------------------------------------------------------------------
10   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
                                                                             |X|

--------------------------------------------------------------------------------
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     9.99%
--------------------------------------------------------------------------------
12   TYPE OF REPORTING PERSON

     IN
--------------------------------------------------------------------------------

----------------------------
         * Based on 13,938,146  shares of the common stock, par value $0.001 per
share (the "Shares") of  BioDelivery  Sciences  International,  Inc., a Delaware
corporation  (the  "Company")  outstanding,  as  represented  in  the  Company's
Quarterly  Report on Form 10-QSB for the period ended  September 30, 2006. As of
December 29, 2006, Laurus Master Fund, Ltd. (the "Fund") held (i) a common stock
purchase  warrant  (the  "January  Warrant #1") to acquire  22,500  Shares at an
exercise price of $0.01 per share, subject to certain adjustments, (ii) a common
stock purchase warrant (the "January Warrant #2") to acquire 39,574 Shares at an
exercise  price of $.01,  subject to certain  adjustments,  (iii) a common stock
purchase  warrant  (the  "January  Warrant #3") to acquire  29,700  Shares at an
exercise  price of $.01,  subject to certain  adjustments;  (iv) a common  stock
purchase  warrant (the  "January  Warrant #4") to acquire  350,000  Shares at an
exercise  price of $3.00,  subject to certain  adjustments,  (v) a common  stock
purchase  warrant (the  "January  Warrant #5") to acquire  483,871  Shares at an
exercise  price of $3.88,  subject to certain  adjustments,  (vi) a common stock
purchase warrant (the "July Warrant #1") to acquire 47,113 Shares at an exercise
price of $3.00,  subject to certain  adjustments;  (vii) a common stock purchase
warrant  (the "July  Warrant #2" and together  with the January  Warrant #1, the
January  Warrant #2, the January Warrant #3, the January Warrant #4, the January
Warrant #5 and the July  Warrant #1, the "Early  Warrants")  to acquire  110,000
Shares, at an exercise price of $3.88, subject to certain adjustments,  (viii) a
common stock  purchase  Warrant (the "December  Warrant #1") to acquire  943,305
Shares, at an exercise price of $3.05, subject to certain  adjustments,  (vii) a
common stock purchase  warrant (the "December  Warrant #2" and together with the
December Warrant #1, the "December  Warrants") to acquire 556,695 Shares,  at an
exercise  price of $3.05 per share,  subject to  certain  adjustments,  (viii) a
Convertible Term Note in the aggregate principal amount of $2,500,000, a portion
of which is convertible  into Shares at a conversion  rate of $2.45,  subject to
certain  adjustments  ("Note #1"); (ix) a Convertible Term Note in the aggregate
principal amount of $2,500,000, a portion of which is convertible into Shares at
a  conversion  rate of $2.45,  subject to certain  adjustments  ("Note #2",  and
together with Note #1, the "Notes");  and (x) 19,403 Shares.  The Early Warrants
and  the  Notes  contain  an  issuance  limitation  prohibiting  the  Fund  from
exercising  those  securities to the extent that such  exercise  would result in
beneficial  ownership  by the Fund of more than 4.99% of the Shares  then issued
and outstanding (the "4.99% Issuance Limitation"). The December Warrants contain
an issuance limitation  prohibiting the Fund from exercising those securities to
the extent that such exercise  would result in beneficial  ownership by the Fund
of more than  9.99% of the  Shares  then  issued  and  outstanding  (the  "9.99%
Issuance  Limitation"  and  together  with the 4.99%  Issuance  Limitation,  the
"Issuance Limitations"). The Issuance Limitations may be waived by the Fund upon
75 days prior notice to the Company and shall automatically become null and void
following notice to the Issuer of the occurrence and/or  continuance of an Event
of  Default  (as  defined  in and  pursuant  to  the  terms  of  the  applicable
instrument).  The Fund is managed by Laurus Capital Management, LLC. Eugene Grin
and David Grin, through other entities, are the controlling principals of Laurus
Capital  Management,  LLC and share sole  voting and  investment  power over the
securities owned by the Fund reported in this Schedule 13G, as amended.






Item 1(a).        Name of Issuer:  BIODELIVERY SCIENCES INTERNATIONAL, INC.


Item 1(b).        Address of Issuer's Principal Executive Offices:
                  185 South Orange Avenue, Administrative Building 4, Newark,
                  New Jersey 07103

Item 2(a).        Name of Person Filing:  Laurus Master Fund, Ltd.

                           This  Schedule  13G,  as  amended,  is also  filed on
                           behalf of Laurus Capital Management,  LLC, a Delaware
                           limited  liability  company,  Eugene  Grin and  David
                           Grin. Laurus Capital  Management,  LLC manages Laurus
                           Master Fund, Ltd. Eugene Grin and David Grin, through
                           other  entities,  are the  controlling  principals of
                           Laurus Capital Management,  LLC and share sole voting
                           and investment  power over the shares owned by Laurus
                           Master  Fund,  Ltd.  Information  related  to each of
                           Laurus Capital Management, LLC, Eugene Grin and David
                           Grin is set forth on Appendix A hereto.

Item 2(b).        Address of Principal Business Office or if none, Residence:
                  c/o Laurus Capital Management, LLC, 825 Third Avenue, 14th
                  Floor, New York, NY 10022

Item 2(c).        Citizenship:  Cayman Islands

Item 2(d).        Title of Class of Securities:  Common Stock

Item 2(e).        CUSIP Number:  09060J106

Item 3.           Not Applicable

Item 4.           Ownership:

         (a)      Amount Beneficially  Owned:  1,392,420 shares of Common Stock*
                  (b) Percent of Class: 9.99%*




         (c)      Number of shares as to which such person has:

                  (i)   sole  power to vote or to direct  the vote:  0 shares of
                        Common Stock*

                  (ii)  shared  power to vote or to direct  the vote:  1,392,420
                        shares of Common Stock*

                  (iii) sole power to dispose or to direct the disposition of: 0
                        shares of Common Stock*

                  (iv)  shared power to dispose or to direct the disposition of:
                        1,392,420 shares of Common Stock*

Item 5.           Ownership of Five Percent or Less of a Class: Not applicable

Item 6.           Ownership  of More than  Five  Percent  on  Behalf of  Another
                  Person: Not applicable

Item 7.           Identification and Classification of Subsidiary Which Acquired
                  the Securities: Not applicable

Item 8.           Identification and Classification of Members of the Group: Not
                  applicable

Item 9.           Notice of Dissolution of Group: Not applicable

Item 10.          Certification:

                  By signing  below I certify  that, to the best of my knowledge
and belief, the securities  referred to above were not acquired and are not held
for the purpose of or with the effect of changing or influencing  the control of
the  issuer  of the  securities  and  were  not  acquired  and are  not  held in
connection  with or as a participant in any  transaction  having that purpose or
effect.

----------------------------
         * Based on 13,938,146  shares of the common stock, par value $0.001 per
share (the "Shares") of  BioDelivery  Sciences  International,  Inc., a Delaware
corporation  (the  "Company")  outstanding,  as  represented  in  the  Company's
Quarterly  Report on Form 10-QSB for the period ended  September 30, 2006. As of
December 29, 2006, Laurus Master Fund, Ltd. (the "Fund") held (i) a common stock
purchase  warrant  (the  "January  Warrant #1") to acquire  22,500  Shares at an
exercise price of $0.01 per share, subject to certain adjustments, (ii) a common
stock purchase warrant (the "January Warrant #2") to acquire 39,574 Shares at an
exercise  price of $.01,  subject to certain  adjustments,  (iii) a common stock
purchase  warrant  (the  "January  Warrant #3") to acquire  29,700  Shares at an
exercise  price of $.01,  subject to certain  adjustments;  (iv) a common  stock
purchase  warrant (the  "January  Warrant #4") to acquire  350,000  Shares at an
exercise  price of $3.00,  subject to certain  adjustments,  (v) a common  stock
purchase  warrant (the  "January  Warrant #5") to acquire  483,871  Shares at an
exercise  price of $3.88,  subject to certain  adjustments,  (vi) a common stock
purchase warrant (the "July Warrant #1") to acquire 47,113 Shares at an exercise
price of $3.00,  subject to certain  adjustments;  (vii) a common stock purchase
warrant  (the "July  Warrant #2" and together  with the January  Warrant #1, the
January  Warrant #2, the January Warrant #3, the January Warrant #4, the January
Warrant #5 and the July  Warrant #1, the "Early  Warrants")  to acquire  110,000
Shares, at an exercise price of $3.88, subject to certain adjustments,  (viii) a
common stock  purchase  Warrant (the "December  Warrant #1") to acquire  943,305
Shares, at an exercise price of $3.05, subject to certain  adjustments,  (vii) a
common stock purchase  warrant (the "December  Warrant #2" and together with the
December Warrant #1, the "December  Warrants") to acquire 556,695 Shares,  at an
exercise  price of $3.05 per share,  subject to  certain  adjustments,  (viii) a
Convertible Term Note in the aggregate principal amount of $2,500,000, a portion
of which is convertible  into Shares at a conversion  rate of $2.45,  subject to
certain  adjustments  ("Note #1"); (ix) a Convertible Term Note in the aggregate
principal amount of $2,500,000, a portion of which is convertible into Shares at
a  conversion  rate of $2.45,  subject to certain  adjustments  ("Note #2",  and
together with Note #1, the "Notes");  and (x) 19,403 Shares.  The Early Warrants
and  the  Notes  contain  an  issuance  limitation  prohibiting  the  Fund  from
exercising  those  securities to the extent that such  exercise  would result in
beneficial  ownership  by the Fund of more than 4.99% of the Shares  then issued
and outstanding (the "4.99% Issuance Limitation"). The December Warrants contain
an issuance limitation  prohibiting the Fund from exercising those securities to
the extent that such exercise  would result in beneficial  ownership by the Fund
of more than  9.99% of the  Shares  then  issued  and  outstanding  (the  "9.99%
Issuance  Limitation"  and  together  with the 4.99%  Issuance  Limitation,  the
"Issuance Limitations"). The Issuance Limitations may be waived by the Fund upon
75 days prior notice to the Company and shall automatically become null and void
following notice to the Issuer of the occurrence and/or  continuance of an Event
of  Default  (as  defined  in and  pursuant  to  the  terms  of  the  applicable
instrument).  The Fund is managed by Laurus Capital Management, LLC. Eugene Grin
and David Grin, through other entities, are the controlling principals of Laurus
Capital  Management,  LLC and share sole  voting and  investment  power over the
securities owned by the Fund reported in this Schedule 13G, as amended.




                                    SIGNATURE

After  reasonable  inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and correct.

                                               January 8, 2007
                                               Date



                                               //s// Eugene Grin
                                               -----------------------------
                                               Eugene Grin
                                               Director







APPENDIX A


A. Name:                            Laurus Capital Management,  LLC, a Delaware
                                    limited liability company
   Business                         825 Third Avenue, 14th Floor
   Address:                         New York, New York 10022
   Place of Organization:           Delaware


B. Name:                            Eugene Grin
   Business                         825 Third Avenue,  14th Floor
   Address:                         New York, New York 10022

   Principal                        Director of Laurus Master Fund, Ltd.
   Occupation:                      Principal of Laurus Capital Management, LLC
   Citizenship:                     United States



C. Name:                            David Grin
   Business                         825 Third Avenue, 14th Floor
   Address:                         New York, New York 10022

   Principal                        Director of Laurus Master Fund, Ltd.
   Occupation:                      Principal of Laurus Capital Management, LLC
   Citizenship:                     Israel










Each of Laurus  Capital  Management,  LLC,  Eugene  Grin and David  Grin  hereby
agrees,  by their execution below,  that the Schedule 13G, as amended,  to which
this Appendix A is attached is filed on behalf of each of them, respectively.

Laurus Capital Management, LLC


  //s// Eugene Grin
------------------------------------------
    Eugene Grin
    Principal
    December 29, 2006



  //s// David Grin
------------------------------------------
    David Grin, on his individual behalf
    December 29, 2006




  //s// Eugene Grin
------------------------------------------
    Eugene Grin, on his individual behalf
    December 29, 2006