Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  ADVANCED TECHNOLOGY VENTURES VII LP
 2. Date of Event Requiring Statement (Month/Day/Year)
06/20/2005		 3. Issuer Name and Ticker or Trading Symbol
CRITICAL THERAPEUTICS INC [CRTX]
(Last)
(First)
(Middle)
1000 WINTER STREET, SUITE 3700		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

WALTHAM, MA 02451		 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 2,554,802
I
By Advanced Technology Ventures VII, L.P. (1)
Common Stock 102,522
I
By Advanced Technology Ventures VII (B), L.P. (2)
Common Stock 49,279
I
By Advanced Technology Ventures VII (C), L.P. (3)
Common Stock 15,225
I
By ATV Entrepreneurs VII, L.P. (4)
Common Stock 427,315
I
By Advanced Technology Ventures VI, L.P. (5)
Common Stock 27,275
I
By ATV Entrepreneurs VI, L.P. (6)
Common Stock 5,714
I
By ATV Alliance 2003, L.P. (7)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Common Stock Warrant (right to buy) 06/20/2005 06/20/2015 Common Stock 359,696 $ 6.58 I By Advanced Technology Ventures VII, L.P. (1)
Common Stock Warrant (right to buy) 06/20/2005 06/20/2015 Common Stock 14,434 $ 6.58 I By Advanced Technology Ventures VII (B), L.P. (2)
Common Stock Warrant (right to buy) 06/20/2005 06/20/2015 Common Stock 6,938 $ 6.58 I By Advanced Technology Ventures VII (C), L.P. (3)
Common Stock Warrant (right to buy) 06/20/2005 06/20/2015 Common Stock 2,144 $ 6.58 I By ATV Entrepreneurs VII, L.P. (4)
Common Stock Warrant (right to buy) 06/20/2005 06/20/2015 Common Stock 60,037 $ 6.58 I By Advanced Technology Ventures VI, L.P. (5)
Common Stock Warrant (right to buy) 06/20/2005 06/20/2015 Common Stock 3,832 $ 6.58 I By ATV Entrepreneurs VI, L.P. (6)

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
ADVANCED TECHNOLOGY VENTURES VII LP
1000 WINTER STREET
SUITE 3700
WALTHAM, MA 02451		     X    
ATV Associates VII, L.L.C.
C/O ADVANCED TECHNOLOGY VENTURES
1000 WINTER STREET, SUITE 3700
WALTHAM, MA 02451		     X    
ATV Associates VI, L.L.C.
C/O ADVANCED TECHNOLOGY VENTURES
1000 WINTER STREET, SUITE 3700
WALTHAM, MA 02451		     X    
Advanced Technology Ventures VI, L.P.
C/O ADVANCED TECHNOLOGY VENTURES
1000 WINTER STREET, SUITE 3700
WALTHAM, MA 02451		     X    
Advanced Technology Ventures VII(B), L.P.
C/O ADVANCED TECHNOLOGY VENTURES
1000 WINTER STREET, SUITE 3700
WALTHAM, MA 02451		     X    
ATV Entrepreneurs VI, L.P.
C/O ADVANCED TECHNOLOGY VENTURES
1000 WINTER STREET, SUITE 3700
WALTHAM, MA 02451		     X    
Advanced Technology Ventures VII(C), L.P.
C/O ADVANCED TECHNOLOGY VENTURES
1000 WINTER STREET, SUITE 3700
WALTHAM, MA 02451		     X    
ATV Alliance 2003, L.P.
C/O ADVANCED TECHNOLOGY VENTURES
1000 WINTER STREET, SUITE 3700
WALTHAM, MA 02451		     X    
ATV Entrepreneurs VII, L.P.
C/O ADVANCED TECHNOLOGY VENTURES
1000 WINTER STREET, SUITE 3700
WALTHAM, MA 02451		     X    
ATV Alliance Associates, L.L.C.
C/O ADVANCED TECHNOLOGY VENTURES
1000 WINTER STREET, SUITE 3700
WALTHAM, MA 02451		     X    

Signatures

By ATV Associates VII, its General Partner, by Jean M. George, Managing Director 11/03/2005
**Signature of Reporting Person Date
By /s/ Jean M. George, Managing Director 11/03/2005
**Signature of Reporting Person Date
By /s/ Pieter Schiller, Managing Director 11/03/2005
**Signature of Reporting Person Date
By ATV Asscociates VI, L.L.C., its General Partner, by /s/ Pieter Schiller, Managing Director 11/03/2005
**Signature of Reporting Person Date
By ATV Asscociates VII, L.L.C., its General Partner, by /s/ Jean M. George, Managing Director 11/03/2005
**Signature of Reporting Person Date
By ATV Asscociates VI, L.L.C., its General Partner, by /s/ Pieter Schiller, Managing Director 11/03/2005
**Signature of Reporting Person Date
By ATV Asscociates VII, L.L.C., its General Partner, by /s/ Jean M. George, Managing Director 11/03/2005
**Signature of Reporting Person Date
By ATV Alliance Asscociates, L.L.C., its General Partner, by /s/ Jean M. George, Manager 11/03/2005
**Signature of Reporting Person Date
By ATV Asscociates VII, L.L.C., its General Partner, by /s/ Jean M. George, Managing Director 11/03/2005
**Signature of Reporting Person Date
By /s/ Jean M. George, Manager 11/03/2005
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The shares are owned by Advanced Technology Ventures VII, L.P. ("ATV VII"), which is under common control with Advanced Technology Ventures VII (B), L.P. ("ATV VII(B)"), Advanced Technology Ventures VII (C), L.P. ("ATV VII(C)") and ATV Entrepreneurs VII, L.P. ("ATVE VII"). ATV Associates VII, L.L.C. serves as the sole general partner of ATV VII, ATV VII(B), ATV VII(C) and ATVE VII. ATV Associates VII, L.L.C. disclaims beneficial ownership of such shares, except to the extent of its pecuniary interest therein.
(2) The shares are owned by ATV VII(B).
(3) The shares are owned by ATV VII(C).
(4) The shares are owned by ATVE VII.
(5) The shares are owned by Advanced Technology Ventures VI, L.P. ("ATV VI"), which is under common control with ATV Entrepreneurs VI, L.P. ("ATVE VI"). ATV Associates VI, L.L.C. serves as the sole general partner of ATV VI and ATVE VI. ATV Associates VI, L.L.C. disclaims beneficial ownership of such shares, except to the extent of its pecuniary interest therein.
(6) The shares are owned by ATVE VI.
(7) The shares are owned by ATV Alliance 2003, L.P. ATV Alliance Associates, L.L.C. is the sole general partner of ATV Alliance 2003, L.P. and ATV Alliance Associates, L.L.C. disclaims beneficial ownership of such shares, except to the extent of its pecuniary interest therein.

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