CUSIP
NO. 02311107
|
Page
2 of 12 Pages
|
1
|
NAMES
OF REPORTING PERSONS
Fountain
Healthcare Partners Fund 1, L.P. (“Fountain”)
|
||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) ¨
(b) ¨
|
||
3
|
SEC
USE ONLY
|
||
4
|
SOURCE
OF FUNDS (See Instructions)
Not
Applicable
|
||
5
|
CHECK
BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d)
OR 2(e) o
|
||
6
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
Ireland
|
||
NUMBER
OF
SHARES
BENEFICIALLY
OWNED
BY
EACH
REPORTING
PERSON
WITH
|
7
|
SOLE
VOTING POWER
0
|
|
8
|
SHARED
VOTING POWER
6,107,087*,
which are directly owned by Fountain. Fountain Healthcare
Partners Ltd. (“Fountain
Partners”), the general partner of Fountain, and each of Manus
Rogan (“Rogan”), a
managing partner of Fountain Partners, Aidan King (“King”), a
managing partner of Fountain Partners, Ena Prosser (“Prosser”), a
partner of Fountain Partners, and Justin Lynch (“Lynch”), a
venture partner and chief financial officer of Fountain Partners, may be
deemed to have shared voting power.
|
||
9
|
SOLE
DISPOSITIVE POWER
0
|
||
10
|
SHARED
DISPOSITIVE POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the
general partner of Fountain, and each of Rogan, a managing partner of
Fountain Partners, King, a managing partner of Fountain Partners, Prosser,
a partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
dispositive power.
|
||
11
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
6,107,087*
|
||
12
|
CHECK
BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
SHARES x
(See
Instructions)
|
||
13
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
6.0%**
|
||
14
|
TYPE
OF REPORTING PERSON (See Instructions)
PN
|
CUSIP
NO. 02311107
|
Page
3 of 12 Pages
|
1
|
NAMES
OF REPORTING PERSONS
Fountain
Healthcare Partners Ltd.
|
||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) ¨
(b) ¨
|
||
3
|
SEC
USE ONLY
|
||
4
|
SOURCE
OF FUNDS (See Instructions)
Not
Applicable
|
||
5
|
CHECK
BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d)
OR 2(e) o
|
||
6
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
Ireland
|
||
NUMBER
OF
SHARES
BENEFICIALLY
OWNED
BY
EACH
REPORTING
PERSON
WITH
|
7
|
SOLE
VOTING POWER
0
|
|
8
|
SHARED
VOTING POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the
general partner of Fountain, and each of Rogan, a managing partner of
Fountain Partners, King, a managing partner of Fountain Partners, Prosser,
a partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
voting power.
|
||
9
|
SOLE
DISPOSITIVE POWER
0
|
||
10
|
SHARED
DISPOSITIVE POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the
general partner of Fountain, and each of Rogan, a managing partner of
Fountain Partners, King, a managing partner of Fountain Partners, Prosser,
a partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
dispositive power.
|
||
11
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
6,107,087*
|
||
12
|
CHECK
BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
SHARES x
(See
Instructions)
|
||
13
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
6.0%**
|
||
14
|
TYPE
OF REPORTING PERSON (See Instructions)
OO
|
CUSIP
NO. 02311107
|
Page
4 of 12 Pages
|
1
|
NAMES
OF REPORTING PERSONS
Manus
Rogan
|
||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) ¨
(b) ¨
|
||
3
|
SEC
USE ONLY
|
||
4
|
SOURCE
OF FUNDS (See Instructions)
Not
Applicable
|
||
5
|
CHECK
BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d)
OR 2(e) o
|
||
6
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
Ireland
|
||
NUMBER
OF
SHARES
BENEFICIALLY
OWNED
BY
EACH
REPORTING
PERSON
WITH
|
7
|
SOLE
VOTING POWER
0
|
|
8
|
SHARED
VOTING POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the
general partner of Fountain, and each of Rogan, a managing partner of
Fountain Partners, King, a managing partner of Fountain Partners, Prosser,
a partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
voting power.
|
||
9
|
SOLE
DISPOSITIVE POWER
0
|
||
10
|
SHARED
DISPOSITIVE POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the
general partner of Fountain, and each of Rogan, a managing partner of
Fountain Partners, King, a managing partner of Fountain Partners, Prosser,
a partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
dispositive power.
|
||
11
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
6,107,087*
|
||
12
|
CHECK
BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
SHARES x
(See
Instructions)
|
||
13
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
6.0%**
|
||
14
|
TYPE
OF REPORTING PERSON (See Instructions)
IN
|
CUSIP
NO. 02311107
|
Page
5 of 12 Pages
|
1
|
NAMES
OF REPORTING PERSONS
Aidan
King
|
||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) ¨
(b) ¨
|
||
3
|
SEC
USE ONLY
|
||
4
|
SOURCE
OF FUNDS (See Instructions)
Not
Applicable
|
||
5
|
CHECK
BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d)
OR 2(e) o
|
||
6
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
Ireland
|
||
NUMBER
OF
SHARES
BENEFICIALLY
OWNED
BY
EACH
REPORTING
PERSON
WITH
|
7
|
SOLE
VOTING POWER
0
|
|
8
|
SHARED
VOTING POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the
general partner of Fountain, and each of Rogan, a managing partner of
Fountain Partners, King, a managing partner of Fountain Partners, Prosser,
a partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
voting power.
|
||
9
|
SOLE
DISPOSITIVE POWER
0
|
||
10
|
SHARED
DISPOSITIVE POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the
general partner of Fountain, and each of Rogan, a managing partner of
Fountain Partners, King, a managing partner of Fountain Partners, Prosser,
a partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
dispositive power.
|
||
11
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
6,107,087*
|
||
12
|
CHECK
BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
SHARES x
(See
Instructions)
|
||
13
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
6.0%**
|
||
14
|
TYPE
OF REPORTING PERSON (See Instructions)
IN
|
CUSIP
NO. 02311107
|
Page
6 of 12 Pages
|
1
|
NAMES
OF REPORTING PERSONS
Ena
Prosser
|
||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) ¨
(b) ¨
|
||
3
|
SEC
USE ONLY
|
||
4
|
SOURCE
OF FUNDS (See Instructions)
Not
Applicable
|
||
5
|
CHECK
BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d)
OR 2(e) o
|
||
6
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
Ireland
|
||
NUMBER
OF
SHARES
BENEFICIALLY
OWNED
BY
EACH
REPORTING
PERSON
WITH
|
7
|
SOLE
VOTING POWER
0
|
|
8
|
SHARED
VOTING POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the
general partner of Fountain, and each of Rogan, a managing partner of
Fountain Partners, King, a managing partner of Fountain Partners, Prosser,
a partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
voting power.
|
||
9
|
SOLE
DISPOSITIVE POWER
0
|
||
10
|
SHARED
DISPOSITIVE POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the
general partner of Fountain, and each of Rogan, a managing partner of
Fountain Partners, King, a managing partner of Fountain Partners, Prosser,
a partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
dispositive power.
|
||
11
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
6,107,087*
|
||
12
|
CHECK
BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
SHARES x
(See
Instructions)
|
||
13
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
6.0%**
|
||
14
|
TYPE
OF REPORTING PERSON (See Instructions)
IN
|
CUSIP
NO. 02311107
|
Page
7 of 12 Pages
|
1
|
NAMES
OF REPORTING PERSONS
Justin
Lynch
|
||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) ¨
(b) ¨
|
||
3
|
SEC
USE ONLY
|
||
4
|
SOURCE
OF FUNDS (See Instructions)
Not
Applicable
|
||
5
|
CHECK
BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d)
OR 2(e) o
|
||
6
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
Ireland
|
||
NUMBER
OF
SHARES
BENEFICIALLY
OWNED
BY
EACH
REPORTING
PERSON
WITH
|
7
|
SOLE
VOTING POWER
0
|
|
8
|
SHARED
VOTING POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the general
partner of Fountain, and each of Rogan, a managing partner of Fountain
Partners, King, a managing partner of Fountain Partners, Prosser, a
partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
voting power.
|
||
9
|
SOLE
DISPOSITIVE POWER
0
|
||
10
|
SHARED
DISPOSITIVE POWER
6,107,087*,
which are directly owned by Fountain. Fountain Partners, the general
partner of Fountain, and each of Rogan, a managing partner of Fountain
Partners, King, a managing partner of Fountain Partners, Prosser, a
partner of Fountain Partners, and Lynch, a venture partner and chief
financial officer of Fountain Partners, may be deemed to have shared
dispositive power.
|
||
11
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
6,107,087*
|
||
12
|
CHECK
BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
SHARES x
(See
Instructions)
|
||
13
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
6.0%**
|
||
14
|
TYPE
OF REPORTING PERSON (See Instructions)
IN
|
CUSIP
NO. 02311107
|
Page
8 of 12 Pages
|
Item
4.
|
Purpose
of Transaction
|
CUSIP
NO. 02311107
|
Page
9 of 12 Pages
|
CUSIP
NO. 02311107
|
Page
10 of 12 Pages
|
Exhibit No.
|
Description:
|
|
Exhibit
E
|
Agreement
of Joint Filing among Fountain Partners Healthcare Fund 1, L.P., Fountain
Healthcare Partners Ltd., Manus Rogan, Aidan King, Ena Prosser and Justin
Lynch.
|
CUSIP
NO. 02311107
|
Page
11 of 12 Pages
|
FOUNTAIN
HEALTHCARE PARTNERS FUND 1, L.P.
|
||||
By:
|
Fountain
Healthcare Partners Ltd.,
|
|||
an
Irish Limited Company
|
||||
Its:
General Partner
|
||||
/s/ Justin Lynch
|
||||
(Signature)
|
||||
Justin Lynch, CFO
|
||||
(Name
and Title)
|
||||
FOUNTAIN
HEALTHCARE PARTNERS LTD.
|
||||
an
Irish Limited Company
|
||||
/s/ Justin Lynch
|
||||
(Signature)
|
||||
Justin Lynch, CFO
|
||||
(Name
and Title)
|
||||
MANUS
ROGAN
|
||||
/s/ Manus Rogan
|
||||
(Signature)
|
||||
AIDAN
KING
|
||||
/s/ Aidan King
|
||||
(Signature)
|
||||
ENA
PROSSER
|
||||
/s/ Ena Prosser
|
||||
(Signature)
|
||||
JUSTIN
LYNCH
|
||||
/s/ Justin Lynch
|
||||
(Signature)
|
FOUNTAIN
HEALTHCARE PARTNERS FUND 1, L.P.
|
||||
By:
|
Fountain
Healthcare Partners Ltd.,
|
|||
an
Irish Limited Company
|
||||
Its:
General Partner
|
||||
/s/ Justin Lynch
|
||||
(Signature)
|
||||
Justin Lynch, CFO
|
||||
(Name
and Title)
|
||||
FOUNTAIN
HEALTHCARE PARTNERS LTD.
|
||||
an
Irish Limited Company
|
||||
/s/ Justin Lynch
|
||||
(Signature)
|
||||
Justin Lynch, CFO
|
||||
(Name
and Title)
|
||||
MANUS
ROGAN
|
||||
/s/ Manus Rogan
|
||||
(Signature)
|
||||
AIDAN
KING
|
||||
/s/ Aidan King
|
||||
(Signature)
|
||||
ENA
PROSSER
|
||||
/s/ Ena Prosser
|
||||
(Signature)
|
||||
JUSTIN
LYNCH
|
||||
/s/ Justin Lynch
|
||||
(Signature)
|